Migratory dendritic cells acquire and present lymphatic endothelial cell-archived antigens during lymph node contraction

Viral infection and vaccination both induce lasting persistence of antigens for protective responses. Here the authors show that migratory dendritic cells, independent of the transcription factor BatF3 for their development, contribute to “archived antigen” exchange with lymphatic endothelial cells....

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Bibliographic Details
Main Authors: Ross M. Kedl, Robin S. Lindsay, Jeffrey M. Finlon, Erin D. Lucas, Rachel S. Friedman, Beth A. Jirón Tamburini
Format: Article
Language:English
Published: Nature Publishing Group 2017-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02247-z
Description
Summary:Viral infection and vaccination both induce lasting persistence of antigens for protective responses. Here the authors show that migratory dendritic cells, independent of the transcription factor BatF3 for their development, contribute to “archived antigen” exchange with lymphatic endothelial cells.
ISSN:2041-1723