Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.

Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.

In our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10-acetoxyangasiol (1), and four other known metabolite...

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Main Authors: Charles Santhanaraju Vairappan, Takahiro Ishii, Tan Kai Lee, Minoru Suzuki, Zhan Zhaoqi
Format: Article
Language:English
Published: MDPI AG 2010-05-01
Series:Marine Drugs
Subjects:
Laurencia sp.
halogenated metabolites
antibacterial activity
Online Access:http://www.mdpi.com/1660-3397/8/6/1743/
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spelling doaj-b553fb45d2974ae2a9f94025b119fd5b2020-11-24T22:44:41ZengMDPI AGMarine Drugs1660-33972010-05-01861743174910.3390/md8061743Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.Charles Santhanaraju VairappanTakahiro IshiiTan Kai LeeMinoru SuzukiZhan ZhaoqiIn our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10-acetoxyangasiol (1), and four other known metabolites, aplysidiol (2), cupalaurenol (3), 1-methyl-2,3,5-tribromoindole (4), and chamigrane epoxide (5), were isolated and identified. Isolated metabolites exhibited potent antibacterial activities against clinical bacteria, Staphylococcus aureus, Staphylococcus sp., Streptococcus pyogenes, Salmonella sp. and Vibrio cholerae. http://www.mdpi.com/1660-3397/8/6/1743/Laurencia sp.halogenated metabolitesantibacterial activity
collection DOAJ
language English
format Article
sources DOAJ
author Charles Santhanaraju Vairappan
Takahiro Ishii
Tan Kai Lee
Minoru Suzuki
Zhan Zhaoqi
spellingShingle Charles Santhanaraju Vairappan
Takahiro Ishii
Tan Kai Lee
Minoru Suzuki
Zhan Zhaoqi
Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.
Marine Drugs
Laurencia sp.
halogenated metabolites
antibacterial activity
author_facet Charles Santhanaraju Vairappan
Takahiro Ishii
Tan Kai Lee
Minoru Suzuki
Zhan Zhaoqi
author_sort Charles Santhanaraju Vairappan
title Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.
title_short Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.
title_full Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.
title_fullStr Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.
title_full_unstemmed Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp.
title_sort antibacterial activities of a new brominated diterpene from borneon laurencia spp.
publisher MDPI AG
series Marine Drugs
issn 1660-3397
publishDate 2010-05-01
description In our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10-acetoxyangasiol (1), and four other known metabolites, aplysidiol (2), cupalaurenol (3), 1-methyl-2,3,5-tribromoindole (4), and chamigrane epoxide (5), were isolated and identified. Isolated metabolites exhibited potent antibacterial activities against clinical bacteria, Staphylococcus aureus, Staphylococcus sp., Streptococcus pyogenes, Salmonella sp. and Vibrio cholerae.
topic Laurencia sp.
halogenated metabolites
antibacterial activity
url http://www.mdpi.com/1660-3397/8/6/1743/
work_keys_str_mv AT charlessanthanarajuvairappan antibacterialactivitiesofanewbrominatedditerpenefromborneonlaurenciaspp
AT takahiroishii antibacterialactivitiesofanewbrominatedditerpenefromborneonlaurenciaspp
AT tankailee antibacterialactivitiesofanewbrominatedditerpenefromborneonlaurenciaspp
AT minorusuzuki antibacterialactivitiesofanewbrominatedditerpenefromborneonlaurenciaspp
AT zhanzhaoqi antibacterialactivitiesofanewbrominatedditerpenefromborneonlaurenciaspp
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