Pitfalls in the Interpretation of Publications about Endoscopic Submucosal Dissection of Early Gastric Cancer with Undifferentiated-Type Histology
Endoscopic submucosal dissection (ESD) is a standard treatment for patients with gastrointestinal neoplasms with a negligible risk of lymph node metastasis. ESD enables en bloc resection of gastrointestinal neoplasms and organ preservation, thereby, avoiding surgical treatment. Although small (<2...
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Hoon Jai Chun
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doaj-b563e9b9945e453490690c8b816946222020-11-25T02:46:21ZengHoon Jai ChunClinical Endoscopy2234-24002234-24432019-01-01521303510.5946/ce.2018.1587188Pitfalls in the Interpretation of Publications about Endoscopic Submucosal Dissection of Early Gastric Cancer with Undifferentiated-Type HistologyChang Seok BangGwang Ho Baik0 Department of Internal Medicine, Hallym University College of Medicine, Chuncheon Sacred Heart Hospital, Chuncheon, KoreaEndoscopic submucosal dissection (ESD) is a standard treatment for patients with gastrointestinal neoplasms with a negligible risk of lymph node metastasis. ESD enables en bloc resection of gastrointestinal neoplasms and organ preservation, thereby, avoiding surgical treatment. Although small (<2 cm) intramucosal early gastric cancer with undifferentiated-type histology (EGC-UH) without ulceration is included in the expanded criteria for ESD, controversies remain due to different biology and characteristics compared to EGC with differentiated-type histology. The authors previously presented studies about the technical feasibility of ESD for these lesions using a meta-analysis and retrospective multicenter analysis. However, many pitfalls were identified in the interpretation of studies analyzing histologic discrepancy, mixed-type histology, criteria-based analysis of therapeutic outcomes, interpretation of curative resection, and long-term clinical outcomes. In this review, the authors discuss pitfalls in the interpretation of publications on ESD for EGC-UH.http://www.e-ce.org/upload/pdf/ce-2018-158.pdfCarcinomaEndoscopic submucosal dissectionUndifferentiated |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chang Seok Bang Gwang Ho Baik |
spellingShingle |
Chang Seok Bang Gwang Ho Baik Pitfalls in the Interpretation of Publications about Endoscopic Submucosal Dissection of Early Gastric Cancer with Undifferentiated-Type Histology Clinical Endoscopy Carcinoma Endoscopic submucosal dissection Undifferentiated |
author_facet |
Chang Seok Bang Gwang Ho Baik |
author_sort |
Chang Seok Bang |
title |
Pitfalls in the Interpretation of Publications about Endoscopic Submucosal Dissection of Early Gastric Cancer with Undifferentiated-Type Histology |
title_short |
Pitfalls in the Interpretation of Publications about Endoscopic Submucosal Dissection of Early Gastric Cancer with Undifferentiated-Type Histology |
title_full |
Pitfalls in the Interpretation of Publications about Endoscopic Submucosal Dissection of Early Gastric Cancer with Undifferentiated-Type Histology |
title_fullStr |
Pitfalls in the Interpretation of Publications about Endoscopic Submucosal Dissection of Early Gastric Cancer with Undifferentiated-Type Histology |
title_full_unstemmed |
Pitfalls in the Interpretation of Publications about Endoscopic Submucosal Dissection of Early Gastric Cancer with Undifferentiated-Type Histology |
title_sort |
pitfalls in the interpretation of publications about endoscopic submucosal dissection of early gastric cancer with undifferentiated-type histology |
publisher |
Hoon Jai Chun |
series |
Clinical Endoscopy |
issn |
2234-2400 2234-2443 |
publishDate |
2019-01-01 |
description |
Endoscopic submucosal dissection (ESD) is a standard treatment for patients with gastrointestinal neoplasms with a negligible risk of lymph node metastasis. ESD enables en bloc resection of gastrointestinal neoplasms and organ preservation, thereby, avoiding surgical treatment. Although small (<2 cm) intramucosal early gastric cancer with undifferentiated-type histology (EGC-UH) without ulceration is included in the expanded criteria for ESD, controversies remain due to different biology and characteristics compared to EGC with differentiated-type histology. The authors previously presented studies about the technical feasibility of ESD for these lesions using a meta-analysis and retrospective multicenter analysis. However, many pitfalls were identified in the interpretation of studies analyzing histologic discrepancy, mixed-type histology, criteria-based analysis of therapeutic outcomes, interpretation of curative resection, and long-term clinical outcomes. In this review, the authors discuss pitfalls in the interpretation of publications on ESD for EGC-UH. |
topic |
Carcinoma Endoscopic submucosal dissection Undifferentiated |
url |
http://www.e-ce.org/upload/pdf/ce-2018-158.pdf |
work_keys_str_mv |
AT changseokbang pitfallsintheinterpretationofpublicationsaboutendoscopicsubmucosaldissectionofearlygastriccancerwithundifferentiatedtypehistology AT gwanghobaik pitfallsintheinterpretationofpublicationsaboutendoscopicsubmucosaldissectionofearlygastriccancerwithundifferentiatedtypehistology |
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1724758897810472960 |