The morphological aspects of the abnormal cardiogenesis in chicks after ethanol treatment: the correlations between whole embryo and heart development

• Main Authors: Маshtalir M.А., Тverdokhleb І.V.
• Format: Article
• Language: Russian
• Published: Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy 2008-01-01
• Series: Морфологія
• Subjects: heart; chick embryo; ethanol; abnomal development; growth retardation
• Online Access: http://www.morphology.dp.ua/_pub/MORPHO-2008-02-02/08mmarrs.pdf

The purpose of the current study was to determine the morphological changes in heart chambers and reveal the types of abnormalities depending on the growth retardation of embryo and extracardiac anomalies. The chick embryos of broilers of Cobb 500 cross were treated by 0,2-0,25 ml 50% ethanol at the beginning of 4 days of incubation, embryos were taken in the end of 4, 5 and 7 days. We revealed the following types of abnormal development of heart mostly with retardation of whole heart or its some parts development: 1) without heart anomalies and normal development of embryo; 2) with heart anomalies and normal development of embryo; 3) without heart anomalies with growth retardation of embryo; 4) with heart anomalies and growth retardation of embryo; 5) with heart anomalies with anomalous development of the whole embryo without retardation; 6) with heart anomalies with anomalous and disturbed development of embryo. Most frequent types were a 4 and 6, the rarest – 1 and 3. We suggest that the growth retardation of embryo and exracardial abnormalities increase the risk of cardiac anomalies.