NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells

NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells

Abstract Background This study was performed to investigate the role of nucleotide-binding oligomerization domain (NOD)-like receptor X1 (NLRX1) in regulating hepatocellular carcinoma (HCC) progression. Methods Expression levels of NLRX1 in clinical specimens and cell lines were determined by revers...

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Bibliographic Details
Main Authors:	Bo Hu, Guang-Yu Ding, Pei-Yao Fu, Xiao-Dong Zhu, Yuan Ji, Guo-Ming Shi, Ying-Hao Shen, Jia-Bin Cai, Zhen Yang, Jian Zhou, Jia Fan, Hui-Chuan Sun, Ming Kuang, Cheng Huang
Format:	Article
Language:	English
Published:	BMC 2018-02-01
Series:	Journal of Hematology & Oncology
Subjects:	Hepatocellular carcinoma NLRX1 Epithelial-mesenchymal-transition Tumor suppressor Senescence Transition
Online Access:	http://link.springer.com/article/10.1186/s13045-018-0573-9

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