Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, China

We identified 2 methicillin-resistant Staphylococcus aureus strains of sequence type 398 from surgical site infections in China. Genetic analysis and clinical data from these strains suggested that they were human-related but sporadic. Hemolysis analysis and mouse-skin infection models indicated a h...

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Main Authors: Lu Sun, Yan Chen, Danying Wang, Haiping Wang, Dandan Wu, Keren Shi, Ping Yan, Yunsong Yu
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2019-01-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/25/1/17-1862_article
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spelling doaj-b5b03fc19c22492b989b60e0101168fe2020-11-25T01:35:12ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592019-01-0125115716010.3201/eid2501.171862Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, ChinaLu SunYan ChenDanying WangHaiping WangDandan WuKeren ShiPing YanYunsong YuWe identified 2 methicillin-resistant Staphylococcus aureus strains of sequence type 398 from surgical site infections in China. Genetic analysis and clinical data from these strains suggested that they were human-related but sporadic. Hemolysis analysis and mouse-skin infection models indicated a high virulence potential for these strains.https://wwwnc.cdc.gov/eid/article/25/1/17-1862_articleMRSAST398surgical site infectioncore genome MLSTvirulencebacteria
collection DOAJ
language English
format Article
sources DOAJ
author Lu Sun
Yan Chen
Danying Wang
Haiping Wang
Dandan Wu
Keren Shi
Ping Yan
Yunsong Yu
spellingShingle Lu Sun
Yan Chen
Danying Wang
Haiping Wang
Dandan Wu
Keren Shi
Ping Yan
Yunsong Yu
Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, China
Emerging Infectious Diseases
MRSA
ST398
surgical site infection
core genome MLST
virulence
bacteria
author_facet Lu Sun
Yan Chen
Danying Wang
Haiping Wang
Dandan Wu
Keren Shi
Ping Yan
Yunsong Yu
author_sort Lu Sun
title Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, China
title_short Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, China
title_full Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, China
title_fullStr Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, China
title_full_unstemmed Surgical Site Infections Caused by Highly Virulent Methicillin-Resistant Staphylococcus aureus Sequence Type 398, China
title_sort surgical site infections caused by highly virulent methicillin-resistant staphylococcus aureus sequence type 398, china
publisher Centers for Disease Control and Prevention
series Emerging Infectious Diseases
issn 1080-6040
1080-6059
publishDate 2019-01-01
description We identified 2 methicillin-resistant Staphylococcus aureus strains of sequence type 398 from surgical site infections in China. Genetic analysis and clinical data from these strains suggested that they were human-related but sporadic. Hemolysis analysis and mouse-skin infection models indicated a high virulence potential for these strains.
topic MRSA
ST398
surgical site infection
core genome MLST
virulence
bacteria
url https://wwwnc.cdc.gov/eid/article/25/1/17-1862_article
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