Pluripotent anti-inflammatory immunomodulatory effects of papaverine against cerebral ischemic-reperfusion injury

Pluripotent anti-inflammatory immunomodulatory effects of papaverine against cerebral ischemic-reperfusion injury

The mechanism of the papaverine (PV) for the treatment of cerebral ischemia remains unclear. A total of 42 mice induced with focal cerebral ischemia were randomly divided into three groups: PV,baicalin (BA)and vehicle group. Both PV and BA could significantly reduce the ischemic infarct volume (P &l...

Full description

Bibliographic Details
Main Authors:	Shuang Guan, Qiong Liu, Hao Gu, Ying-ying Zhang, Peng-lu Wei, Yi-fei Qi, Jun Liu, Zhong Wang
Format:	Article
Language:	English
Published:	Elsevier 2020-10-01
Series:	Journal of Pharmacological Sciences
Subjects:	Papaverine Cerebral ischemia Ischemic-reperfusion Anti-inflammation Immune response
Online Access:	http://www.sciencedirect.com/science/article/pii/S1347861320300724

Similar Items

The protective effect of Papaverine and Alprostadil in rat testes after ischemia and reperfusion injury
by: Mehmet Ali Karagoz, et al.

The effect of irrigation of intracisternal papaverine on cerebral blood flow in subarachnoid hemorrhage
by: Masih Sabouri, et al.
Published: (2013-01-01)

Danhong injection alleviates cerebral ischemia/reperfusion injury by improving intracellular energy metabolism coupling in the ischemic penumbra
by: Miaolin Zeng, et al.
Published: (2021-08-01)

Avoiding Liver Injury with Papaverine and Ascorbic Acid Due to Infrarenal Cross-Clamping: an Experimental Study
by: Serhat Huseyin, et al.

Effect of Papaverine on Human Serum Albumin Glycation
by: A Ahmadzadeh, et al.
Published: (2012-05-01)

Papaverine use for radial artery sheath entrapment
by: Alessandro Sciahbasi, et al.
Published: (2019-06-01)

Enriched Environment Attenuates Pyroptosis to Improve Functional Recovery After Cerebral Ischemia/Reperfusion Injury
by: Jingying Liu, et al.
Published: (2021-09-01)

Topical intraperitoneal papaverine to minimize non-viable bowel resection from non-occlusive bowel ischemia in neonatal segmental volvulus: A case report
by: Roger Chen Zhu, et al.
Published: (2016-10-01)

Neuroprotective Effects of Pregabalin on Cerebral Ischemia and Reperfusion
by: Sanem Aşçı, et al.
Published: (2016-04-01)

Antiproliferative Effect of the Isoquinoline Alkaloid Papaverine in Hepatocarcinoma HepG-2 Cells — Inhibition of Telomerase and Induction of Senescence
by: Sakineh Kazemi Noureini, et al.
Published: (2014-08-01)

Neuroprotective effects of irisin against cerebral ischemia/ reperfusion injury via Notch signaling pathway
by: Zhao Jin, et al.
Published: (2019-12-01)

The influence of stachydrine hydrochloride on the reperfusion model of mice with repetitive cerebral ischemia
by: Mingsan Miao, et al.
Published: (2017-03-01)

Effects of Remote Ischemic Conditioning Methods on Ischemia-Reperfusion Injury in Muscle Flaps: An Experimental Study in Rats
by: Durdane Keskin, et al.
Published: (2017-09-01)

Papaverine inhibits lipopolysaccharide-induced microglial activation by suppressing NF-κB signaling pathway
by: Dang Y, et al.
Published: (2016-02-01)

Papaverine is a confounding factor in neurological assessment after cerebral aneurysm clipping: Report of three cases and review of the literature
by: Veena Sheshadri, et al.
Published: (2016-01-01)

Analysis of the neuroprotective effect of GLP‐1 receptor agonist peptide on cerebral ischemia‐reperfusion injury by Quantitative Proteomics Mass Spectrometry
by: Ying Li, et al.
Published: (2021-06-01)

Effect of Panax notoginseng Saponins on Focal Cerebral Ischemia-Reperfusion in Rat Models: A Meta-Analysis
by: Tao Sun, et al.
Published: (2021-02-01)

Effects of parenteral papaverine and piracetam administration on cochlea following acoustic trauma
by: Nurcan Yurtsever Kum, et al.
Published: (2018-01-01)

Protective Effect of Ischemic Postconditioning against Ischemia Reperfusion-Induced Myocardium Oxidative Injury in IR Rats
by: Jiangwei Ma, et al.
Published: (2012-03-01)

Intracisternal papaverine toxicity in anterior circulation aneurysm clipping surgery
by: Zahraa F. Al-Sharshahi, et al.
Published: (2020-09-01)

ST elevation after intracoronary administration of Papaverine for fractional flow reserve estimation
by: R.K. Jain, et al.
Published: (2014-05-01)

Electrophysiological Effects of Bosentan in Rats with Induced Cerebral Ischemia-Reperfusion
by: Bekir Akgun, et al.
Published: (2013-08-01)

MicroRNAs Regulate Mitochondrial Function in Cerebral Ischemia-Reperfusion Injury
by: Yue Hu, et al.
Published: (2015-10-01)

The effect of morphine delta receptor activity on ischemic postconditioning in lung ischemia reperfusion injury
by: Nuri Duzgun, et al.
Published: (2018-01-01)

The neuroprotective effect of pretreatment with carbon dots from Crinis Carbonisatus (carbonized human hair) against cerebral ischemia reperfusion injury
by: Yue Zhang, et al.
Published: (2021-08-01)

FKBP5 Exacerbates Impairments in Cerebral Ischemic Stroke by Inducing Autophagy via the AKT/FOXO3 Pathway
by: Shijia Yu, et al.
Published: (2020-07-01)

Influences of ischemic postconditioning at different positions on oxidative stress of myocardial ischemia-reperfusion injury in rats
by: Chao Wan, et al.
Published: (2021-03-01)

Combined use of ischemic preconditioning and postconditioning in a skin flap model in rats
by: Asim Uslu, et al.
Published: (2019-01-01)

Anti-cerebral ischemia reperfusion injury of polysaccharides: A review of the mechanisms
by: Qianghua Yuan, et al.
Published: (2021-05-01)

Novel Papaverine Metal Complexes with Potential Anticancer Activities
by: Ahmed Gaber, et al.
Published: (2020-11-01)

A Protective Effect of Ischemic Preconditioning on the Rat Lung Ischemia-Reperfusion Injury
by: Sacit Coban, et al.
Published: (2014-12-01)

The role of ischemic preconditioning in the expression of apoptosis-related genes in a rat model of intestinal ischemia-reperfusion injury
by: Celina Teresa Castelo Branco Couto de Miranda, et al.

Ischemia preconditioning is neuroprotective in a rat cerebral ischemic injury model through autophagy activation and apoptosis inhibition
by: D.Y. Xia, et al.
Published: (2013-08-01)

Effect of papaverine combined with tirofiban intracoronary injection on the degree of myocardial injury in patients with no reflow during PCI
by: De-Yin Zeng, et al.
Published: (2018-09-01)

Ischemic postconditioning ameliorates acute kidney injury induced by limb ischemia/reperfusion via transforming TLR4 and NF-κB signaling in rats
by: Zhongdi Liu, et al.
Published: (2021-07-01)

Effect of papaverine hydrochloride solution on survival rate of neural-island flap in experiment
by: A. V. Baytinger, et al.
Published: (2010-12-01)

Peak systolic velocity of cavernosal artery of the penis before and after papaverine injection in erectile dysfunction
by: Bagheri SM, et al.
Published: (2012-08-01)

Ischemic pre and postconditioning in skeletal muscle injury produced by ischemia and reperfusion in rats
by: José Alves Lintz, et al.
Published: (2013-06-01)

Neuroprotective Mechanisms of Calycosin Against Focal Cerebral Ischemia and Reperfusion Injury in Rats
by: Yong Wang, et al.
Published: (2018-01-01)

Neuroprotective effects of curdione against focal cerebral ischemia reperfusion injury in rats
by: Li XJ, et al.
Published: (2017-06-01)