Occurrence of thymic pathology in two families. Is familial screening justified?

• Main Authors: Sotirios D. Moraitis, Apostolos C. Agrafiotis, Amalia Kapranou, Marina Constantinou, Konstantinos Kanakakis, Panagiotis Hountis
• Format: Article
• Language: English
• Published: PAGEPress Publications 2018-09-01
• Series: Monaldi Archives for Chest Disease
• Subjects: Familial; thymoma; thymic carcinoma; thymic hyperplasia.
• Online Access: https://www.monaldi-archives.org/index.php/macd/article/view/913

The familial occurrence of thymic pathology, even though rare, is widely reported in the literature and mainly concerns cases of familial autoimmune myasthenia gravis. Other less frequent cases of familial occurrence of thymoma, thymic carcinoid and thymic hyperplasia have been described. It seems that the familial occurrence is poorly recorded and thus its prevalence is underestimated. We report two families whose members presented different forms of thymic pathology and discuss the necessity of screening programs in family members of patients presenting a thymic lesion.