Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography
Objective: Menopause is a physiological life period that potentially affects various organs and systems. Therefore, a wide spectrum of signs and symptoms of eyes may be clinically observed in the postmenopausal period. Aim of the study : To evaluate the macular, retinal nerve fiber layer (RNFL)...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Termedia Publishing House
2014-03-01
|
Series: | Menopause Review |
Subjects: | |
Online Access: | http://www.termedia.pl/Evaluation-of-the-macula-retinal-nerve-fiber-layer-and-choroid-thickness-in-postmenopausal-women-and-reproductive-age-women-using-spectral-domain-optical-coherence-tomography,4,22418,1,1.html |
id |
doaj-b5c6ee368b6e4a4a94704ad45ffa69ba |
---|---|
record_format |
Article |
spelling |
doaj-b5c6ee368b6e4a4a94704ad45ffa69ba2020-11-24T22:45:56ZengTermedia Publishing HouseMenopause Review1643-88762299-00382014-03-01131364110.5114/pm.2014.4108822418Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomographyMustafa AtaşGökhan AçmazHüseyin AksoySüleyman DemircanAltan GöktaşHasan Basri ArifoğluGökmen ZararsızObjective: Menopause is a physiological life period that potentially affects various organs and systems. Therefore, a wide spectrum of signs and symptoms of eyes may be clinically observed in the postmenopausal period. Aim of the study : To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in postmenopausal women and compare with healthy reproductive-age women controls. Material and methods: The study population included a healthy reproductive-age control group (n = 72) and postmenopausal study group (n = 72). Retinal thickness parameters were measured by SD-OCT. Peripapillary RNFL thickness parameters, macular thickness and choroidal thickness were evaluated. Results : Superior inner macula, temporal inner macula, inferior inner macula, nasal inner macula, inferior outer macula and choroid thickness were significantly thinner in the postmenopausal study group than the healthy reproductive-age control group (p = 0.007, p = 0.037, p = 0.027, p = 0.006, p = 0.016, p < 0.001, respectively). After adjusting for age, only choroid thickness was significantly thinner in the postmenopausal study group than controls (p† = 0.005). Conclusions : This study revealed that choroidal thickness measured by SD-OCT was significantly thinner in postmenopausal women than healthy reproductive-age women. We can speculate that the decrease in choroidal thickness in postmenopausal women may indicate a reduced estrogen-dependent vasodilatory effect in ophthalmic artery secondary to menopausal estrogen deficiency.http://www.termedia.pl/Evaluation-of-the-macula-retinal-nerve-fiber-layer-and-choroid-thickness-in-postmenopausal-women-and-reproductive-age-women-using-spectral-domain-optical-coherence-tomography,4,22418,1,1.htmlmacula retinal nerve fiber layer choroid menopause optical coherence tomography |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mustafa Ataş Gökhan Açmaz Hüseyin Aksoy Süleyman Demircan Altan Göktaş Hasan Basri Arifoğlu Gökmen Zararsız |
spellingShingle |
Mustafa Ataş Gökhan Açmaz Hüseyin Aksoy Süleyman Demircan Altan Göktaş Hasan Basri Arifoğlu Gökmen Zararsız Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography Menopause Review macula retinal nerve fiber layer choroid menopause optical coherence tomography |
author_facet |
Mustafa Ataş Gökhan Açmaz Hüseyin Aksoy Süleyman Demircan Altan Göktaş Hasan Basri Arifoğlu Gökmen Zararsız |
author_sort |
Mustafa Ataş |
title |
Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography |
title_short |
Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography |
title_full |
Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography |
title_fullStr |
Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography |
title_full_unstemmed |
Evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography |
title_sort |
evaluation of the macula, retinal nerve fiber layer and choroid thickness in postmenopausal women and reproductive-age women using spectral-domain optical coherence tomography |
publisher |
Termedia Publishing House |
series |
Menopause Review |
issn |
1643-8876 2299-0038 |
publishDate |
2014-03-01 |
description |
Objective: Menopause is a physiological life period that potentially affects various organs and systems. Therefore, a wide spectrum of signs and symptoms of eyes may be clinically observed in the postmenopausal period.
Aim of the study : To evaluate the macular, retinal nerve fiber layer (RNFL) and choroidal thickness alterations by using spectral-domain optical coherence tomography (SD-OCT) in postmenopausal women and compare with healthy reproductive-age women controls.
Material and methods: The study population included a healthy reproductive-age control group (n = 72) and postmenopausal study group (n = 72). Retinal thickness parameters were measured by SD-OCT. Peripapillary RNFL thickness parameters, macular thickness and choroidal thickness were evaluated.
Results : Superior inner macula, temporal inner macula, inferior inner macula, nasal inner macula, inferior outer macula and choroid thickness were significantly thinner in the postmenopausal study group than the healthy reproductive-age control group (p = 0.007, p = 0.037, p = 0.027, p = 0.006, p = 0.016, p < 0.001, respectively). After adjusting for age, only choroid thickness was significantly thinner in the postmenopausal study group than controls (p† = 0.005).
Conclusions : This study revealed that choroidal thickness measured by SD-OCT was significantly thinner in postmenopausal women than healthy reproductive-age women. We can speculate that the decrease in choroidal thickness in postmenopausal women may indicate a reduced estrogen-dependent vasodilatory effect in ophthalmic artery secondary to menopausal estrogen deficiency. |
topic |
macula retinal nerve fiber layer choroid menopause optical coherence tomography |
url |
http://www.termedia.pl/Evaluation-of-the-macula-retinal-nerve-fiber-layer-and-choroid-thickness-in-postmenopausal-women-and-reproductive-age-women-using-spectral-domain-optical-coherence-tomography,4,22418,1,1.html |
work_keys_str_mv |
AT mustafaatas evaluationofthemacularetinalnervefiberlayerandchoroidthicknessinpostmenopausalwomenandreproductiveagewomenusingspectraldomainopticalcoherencetomography AT gokhanacmaz evaluationofthemacularetinalnervefiberlayerandchoroidthicknessinpostmenopausalwomenandreproductiveagewomenusingspectraldomainopticalcoherencetomography AT huseyinaksoy evaluationofthemacularetinalnervefiberlayerandchoroidthicknessinpostmenopausalwomenandreproductiveagewomenusingspectraldomainopticalcoherencetomography AT suleymandemircan evaluationofthemacularetinalnervefiberlayerandchoroidthicknessinpostmenopausalwomenandreproductiveagewomenusingspectraldomainopticalcoherencetomography AT altangoktas evaluationofthemacularetinalnervefiberlayerandchoroidthicknessinpostmenopausalwomenandreproductiveagewomenusingspectraldomainopticalcoherencetomography AT hasanbasriarifoglu evaluationofthemacularetinalnervefiberlayerandchoroidthicknessinpostmenopausalwomenandreproductiveagewomenusingspectraldomainopticalcoherencetomography AT gokmenzararsız evaluationofthemacularetinalnervefiberlayerandchoroidthicknessinpostmenopausalwomenandreproductiveagewomenusingspectraldomainopticalcoherencetomography |
_version_ |
1725686977632665600 |