A mouse model of post-arthroplasty Staphylococcus aureus joint infection to evaluate in vivo the efficacy of antimicrobial implant coatings.
Post-arthroplasty infections represent a devastating complication of total joint replacement surgery, resulting in multiple reoperations, prolonged antibiotic use, extended disability and worse clinical outcomes. As the number of arthroplasties in the U.S. will exceed 3.8 million surgeries per year...
Main Authors: | Nicholas M Bernthal, Alexandra I Stavrakis, Fabrizio Billi, John S Cho, Thomas J Kremen, Scott I Simon, Ambrose L Cheung, Gerald A Finerman, Jay R Lieberman, John S Adams, Lloyd S Miller |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-09-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2935351?pdf=render |
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