The Reactions of H<sub>2</sub>O<sub>2</sub> and GSNO with the Zinc Finger Motif of XPA. Not A Regulatory Mechanism, But No Synergy with Cadmium Toxicity

The Reactions of H<sub>2</sub>O<sub>2</sub> and GSNO with the Zinc Finger Motif of XPA. Not A Regulatory Mechanism, But No Synergy with Cadmium Toxicity

Tetrathiolate zinc fingers are potential targets of oxidative assault under cellular stress conditions. We used the synthetic 37-residue peptide representing the tetrathiolate zinc finger domain of the DNA repair protein XPA, acetyl-DYVICEECGKEFMSYLMNHFDLPTCDNCRDADDKHK-amide (XPAzf) as a working mod...

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Bibliographic Details
Main Authors:	Aleksandra Witkiewicz-Kucharczyk, Wojciech Goch, Jacek Olędzki, Andrea Hartwig, Wojciech Bal
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	Molecules
Subjects:	zinc fingers zinc cadmium hydrogen peroxide S-nitrosoglutathione oxidation
Online Access:	https://www.mdpi.com/1420-3049/25/18/4177

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