The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer?
The hedgehog (Hh) pathway plays a key role in embryonic development and stem cell programs. Deregulation of the Hh pathway is a key driver of basal cell carcinoma, and therapeutic targeting led to approval of Hh inhibitor, vismodegib, in the management of this cancer. The Hh pathway is implicated in...
Main Authors: | Priyanka Bhateja, Mathew Cherian, Sarmila Majumder, Bhuvaneswari Ramaswamy |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-08-01
|
Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/8/1126 |
Similar Items
-
Targeting the Hedgehog Pathway in Pediatric Medulloblastoma
by: Sherri Y. Huang, et al.
Published: (2015-10-01) -
Regulation of Gli proteins by the Hedgehog Signaling Pathway
by: Lopez, Lyle Villamater
Published: (2013) -
Hedgehog Signaling Inhibitors as Anti-Cancer Agents in Osteosarcoma
by: Ram Mohan Ram Kumar, et al.
Published: (2015-05-01) -
Targeting the Hedgehog Pathway in Cancer: Current Evidence and Future Perspectives
by: Daniel Girardi, et al.
Published: (2019-02-01) -
Analyse des Hedgehog-Signalweges in Zellkulturen maligner Gliome
by: Braun, Stefanie Anett
Published: (2013)