Chitosan/Polycyclodextrin (CHT/PCD)-Based Sponges Delivering VEGF to Enhance Angiogenesis for Bone Regeneration

Chitosan/Polycyclodextrin (CHT/PCD)-Based Sponges Delivering VEGF to Enhance Angiogenesis for Bone Regeneration

Vascularization is one of the main challenges in bone tissue engineering (BTE). In this study, vascular endothelial growth factor (VEGF), known for its angiogenic effect, was delivered by our developed sponge, derived from a polyelectrolyte complexes hydrogel between chitosan (CHT) and <i>anio...

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Bibliographic Details
Main Authors: Carla Palomino-Durand, Marco Lopez, Pierre Marchandise, Bernard Martel, Nicolas Blanchemain, Feng Chai
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Pharmaceutics
Subjects:
sponges
cyclodextrin polymer
chitosan
VEGF-delivery
bone tissue engineering
cell migration
Online Access:https://www.mdpi.com/1999-4923/12/9/784

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