Metformin: A Prospective Alternative for the Treatment of Chronic Pain

Metformin: A Prospective Alternative for the Treatment of Chronic Pain

Metformin (biguanide) is a drug widely used for the treatment of type 2 diabetes. This drug has been used for 60 years as a highly effective antihyperglycemic agent. The search for the mechanism of action of metformin has produced an enormous amount of research to explain its effects on gluconeogene...

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Bibliographic Details
Main Authors: Guadalupe Del Carmen Baeza-Flores, Crystell Guadalupe Guzmán-Priego, Leonor Ivonne Parra-Flores, Janet Murbartián, Jorge Elías Torres-López, Vinicio Granados-Soto
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Pharmacology
Subjects:
anxiety
AMPK activation
chronic pain
metformin
depression
neuropathic pain
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.558474/full

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