Standardized tensile testing of soft tissue using a 3D printed clamping system
Biomechanical testing of soft tissues forms the backbone in the experimental validation of tissue engineering and for modelling purposes. The standardized testing of soft tissues requires different experimental protocols and fixtures compared to hard tissues or non-biological materials due to their...
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doaj-b63c4cc24c454ad6979b4beddf66fb982020-12-25T05:11:14ZengElsevierHardwareX2468-06722020-10-018e00159Standardized tensile testing of soft tissue using a 3D printed clamping systemMario Scholze0Sarah Safavi1Kai Chun Li2Benjamin Ondruschka3Michael Werner4Johann Zwirner5Niels Hammer6Institute of Materials Science and Engineering, Chemnitz University of Technology, Chemnitz, Germany; Department of Clinical and Macroscopic Anatomy, Medical University of Graz, Graz, Austria; Corresponding author.Department of Anatomy, University of Otago, Dunedin, New ZealandDepartment of Oral Rehabilitation, Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New ZealandInstitute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, GermanyFraunhofer Institute for Machine Tools and Forming Technology IWU, Dresden, Germany; Institute of Anatomy, University of Leipzig, Leipzig, GermanyDepartment of Anatomy, University of Otago, Dunedin, New ZealandDepartment of Clinical and Macroscopic Anatomy, Medical University of Graz, Graz, Austria; Fraunhofer Institute for Machine Tools and Forming Technology IWU, Dresden, Germany; Department of Orthopedic and Trauma Surgery, University of Leipzig, Leipzig, Germany; Corresponding author.Biomechanical testing of soft tissues forms the backbone in the experimental validation of tissue engineering and for modelling purposes. The standardized testing of soft tissues requires different experimental protocols and fixtures compared to hard tissues or non-biological materials due to their characteristics. Some of the most commonly-used clamping methods for soft tissue testing affect the tissues’ mechanical properties as chemicals are involved to decelerate degradation and autolysis. Moreover, they are unsuitable for standardized and high-throughput testing. Material slippage is also a recurrent unwanted influence on the testing routine with impact on measurement validity. Addressing these issues, this protocol presents a clamping system for simplified testing of biological soft tissues with all necessary components manufactured utilizing 3D printing technology. Templates allow trimming the samples into standardized shapes and sizes while preparation tables facilitate clamping in a fixed distance. The key parts of the system are clamps with a pyramid design, which allow the mounting of biological soft tissues before transferring it into the testing device and minimize material slippage during tensile testing. Flexible holder arms are used to transfer samples from preparation tables into the testing device and simplify positioning. Mechanical testing itself is performed with digital image correlation for precise strain measurements.http://www.sciencedirect.com/science/article/pii/S24680672203006873D printingBiomechanical testingClampsSoft tissuesTensile testing |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mario Scholze Sarah Safavi Kai Chun Li Benjamin Ondruschka Michael Werner Johann Zwirner Niels Hammer |
spellingShingle |
Mario Scholze Sarah Safavi Kai Chun Li Benjamin Ondruschka Michael Werner Johann Zwirner Niels Hammer Standardized tensile testing of soft tissue using a 3D printed clamping system HardwareX 3D printing Biomechanical testing Clamps Soft tissues Tensile testing |
author_facet |
Mario Scholze Sarah Safavi Kai Chun Li Benjamin Ondruschka Michael Werner Johann Zwirner Niels Hammer |
author_sort |
Mario Scholze |
title |
Standardized tensile testing of soft tissue using a 3D printed clamping system |
title_short |
Standardized tensile testing of soft tissue using a 3D printed clamping system |
title_full |
Standardized tensile testing of soft tissue using a 3D printed clamping system |
title_fullStr |
Standardized tensile testing of soft tissue using a 3D printed clamping system |
title_full_unstemmed |
Standardized tensile testing of soft tissue using a 3D printed clamping system |
title_sort |
standardized tensile testing of soft tissue using a 3d printed clamping system |
publisher |
Elsevier |
series |
HardwareX |
issn |
2468-0672 |
publishDate |
2020-10-01 |
description |
Biomechanical testing of soft tissues forms the backbone in the experimental validation of tissue engineering and for modelling purposes. The standardized testing of soft tissues requires different experimental protocols and fixtures compared to hard tissues or non-biological materials due to their characteristics. Some of the most commonly-used clamping methods for soft tissue testing affect the tissues’ mechanical properties as chemicals are involved to decelerate degradation and autolysis. Moreover, they are unsuitable for standardized and high-throughput testing. Material slippage is also a recurrent unwanted influence on the testing routine with impact on measurement validity. Addressing these issues, this protocol presents a clamping system for simplified testing of biological soft tissues with all necessary components manufactured utilizing 3D printing technology. Templates allow trimming the samples into standardized shapes and sizes while preparation tables facilitate clamping in a fixed distance. The key parts of the system are clamps with a pyramid design, which allow the mounting of biological soft tissues before transferring it into the testing device and minimize material slippage during tensile testing. Flexible holder arms are used to transfer samples from preparation tables into the testing device and simplify positioning. Mechanical testing itself is performed with digital image correlation for precise strain measurements. |
topic |
3D printing Biomechanical testing Clamps Soft tissues Tensile testing |
url |
http://www.sciencedirect.com/science/article/pii/S2468067220300687 |
work_keys_str_mv |
AT marioscholze standardizedtensiletestingofsofttissueusinga3dprintedclampingsystem AT sarahsafavi standardizedtensiletestingofsofttissueusinga3dprintedclampingsystem AT kaichunli standardizedtensiletestingofsofttissueusinga3dprintedclampingsystem AT benjaminondruschka standardizedtensiletestingofsofttissueusinga3dprintedclampingsystem AT michaelwerner standardizedtensiletestingofsofttissueusinga3dprintedclampingsystem AT johannzwirner standardizedtensiletestingofsofttissueusinga3dprintedclampingsystem AT nielshammer standardizedtensiletestingofsofttissueusinga3dprintedclampingsystem |
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