Radiofrequency Catheter Ablation of Idiopathic Right Ventricular Outflow Tract Arrhythmias

• Main Authors: Naiara Calvo, MD, Monique Jongbloed, MD, PhD, Katja Zeppenfeld, MD, PhD
• Format: Article
• Language: English
• Published: Elsevier 2013-01-01
• Series: Indian Pacing and Electrophysiology Journal
• Subjects: ventricular arrhythmias; outflow tract; premature ventricular contractions; ablation
• Online Access: http://www.sciencedirect.com/science/article/pii/S097262921630585X

Idiopathic ventricular arrhythmias (VA) consist of various subtypes of VA that occur in the absence of clinically apparent structural heart disease. Affected patients account for approximately 10% of all patients referred for evaluation of ventricular tachycardia (VT). Arrhythmias arising from the outflow tract (OT) are the most common subtype of idiopathic VA and more than 70–80% of idiopathic VTs or premature ventricular contractions (PVCs) originate from the right ventricular (RV) OT. Idiopathic OT arrhythmias are thought to be caused by adenosine-sensitive, cyclic adenosine monophosphate (cAMP) mediated triggered activity and, in general, manifest at a relatively early age. Usually they present as salvos of paroxysmal ventricular ectopic beats and are rarely life-threatening. When highly symptomatic and refractory to antiarrhythmic therapy or causative for ventricular dysfunction, ablation is a recommended treatment with a high success rate and a low risk of complications.