Trypanosomatidae codon usage and GC distribution

A study od Typanosomatidae GC distribution and codon usage is presented. The codon usage patterns in coincidence with the phylogenetical data are similar in Crithidia and Leishmania, whereas they are more divergent in Trypanosoma brucei and T. cruzi. The analyisis of the GC mutational pressure in th...

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Bibliographic Details
Main Authors:	Guilhermina Alonso, Palmira Guevara, Jose L. Ramirez
Format:	Article
Language:	English
Published:	Instituto Oswaldo Cruz, Ministério da Saúde 1992-12-01
Series:	Memórias do Instituto Oswaldo Cruz.
Subjects:	Trypanosomatidae codon usage mutational pressure GC content
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000400009

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spelling	doaj-b6647b9b3539461aa117fa28d886fe362020-11-25T00:34:29ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.0074-02761678-80601992-12-0187451752310.1590/S0074-02761992000400009Trypanosomatidae codon usage and GC distributionGuilhermina AlonsoPalmira GuevaraJose L. RamirezA study od Typanosomatidae GC distribution and codon usage is presented. The codon usage patterns in coincidence with the phylogenetical data are similar in Crithidia and Leishmania, whereas they are more divergent in Trypanosoma brucei and T. cruzi. The analyisis of the GC mutational pressure in these organisms reveals that T. brucei, and to a lesser extent T. cruzi, have envolved towards a more balanced use of all bases, whereas Leishmania and Crithidia retain features of a primeval genetic apparatus. Tables with approximated GC mutational pressure in homologous genes, and codon usage in Trypanosomatidae are presented.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000400009Trypanosomatidaecodon usagemutational pressureGC content
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Guilhermina Alonso Palmira Guevara Jose L. Ramirez
spellingShingle	Guilhermina Alonso Palmira Guevara Jose L. Ramirez Trypanosomatidae codon usage and GC distribution Memórias do Instituto Oswaldo Cruz. Trypanosomatidae codon usage mutational pressure GC content
author_facet	Guilhermina Alonso Palmira Guevara Jose L. Ramirez
author_sort	Guilhermina Alonso
title	Trypanosomatidae codon usage and GC distribution
title_short	Trypanosomatidae codon usage and GC distribution
title_full	Trypanosomatidae codon usage and GC distribution
title_fullStr	Trypanosomatidae codon usage and GC distribution
title_full_unstemmed	Trypanosomatidae codon usage and GC distribution
title_sort	trypanosomatidae codon usage and gc distribution
publisher	Instituto Oswaldo Cruz, Ministério da Saúde
series	Memórias do Instituto Oswaldo Cruz.
issn	0074-0276 1678-8060
publishDate	1992-12-01
description	A study od Typanosomatidae GC distribution and codon usage is presented. The codon usage patterns in coincidence with the phylogenetical data are similar in Crithidia and Leishmania, whereas they are more divergent in Trypanosoma brucei and T. cruzi. The analyisis of the GC mutational pressure in these organisms reveals that T. brucei, and to a lesser extent T. cruzi, have envolved towards a more balanced use of all bases, whereas Leishmania and Crithidia retain features of a primeval genetic apparatus. Tables with approximated GC mutational pressure in homologous genes, and codon usage in Trypanosomatidae are presented.
topic	Trypanosomatidae codon usage mutational pressure GC content
url	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000400009
work_keys_str_mv	AT guilherminaalonso trypanosomatidaecodonusageandgcdistribution AT palmiraguevara trypanosomatidaecodonusageandgcdistribution AT joselramirez trypanosomatidaecodonusageandgcdistribution
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Trypanosomatidae codon usage and GC distribution

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