Pretransplant Cardiac Evaluation Using Novel Technology

• Main Authors: Mohamad Hemu, Allison Zimmerman, Dinesh Kalra, Tochukwu Okwuosa
• Format: Article
• Language: English
• Published: MDPI AG 2019-05-01
• Series: Journal of Clinical Medicine
• Subjects: hematopoietic stem cell transplant; cardiac imaging; cardiovascular complications; echocardiogram; cardiac magnetic resonance; speckle tracking echocardiography; coronary computed tomography
• Online Access: https://www.mdpi.com/2077-0383/8/5/690

Hematopoietic stem-cell transplantation (HSCT) is a complex procedure that has been increasingly successful in treating malignant and nonmalignant conditions. Despite its effectiveness, it can be associated with potentially life-threatening adverse effects. New onset heart failure, ischemic disease, and arrhythmias are among the most notable cardiovascular complications post-HSCT. As a result, appropriate cardiac risk stratification prior to transplant could result in decreased morbidity and mortality by identifying patients with a higher probability of tolerating possible toxicities associated with HSCT. In this review, we aim to discuss the utility of cardiac screening using novel modalities of imaging technology in the pre-HSCT phase.