Epigallocatechin-3-gallate suppresses 1-methyl-4-phenyl-pyridine-induced oxidative stress in PC12 cells via the SIRT1/PGC-1α signaling pathway

Epigallocatechin-3-gallate suppresses 1-methyl-4-phenyl-pyridine-induced oxidative stress in PC12 cells via the SIRT1/PGC-1α signaling pathway

<p>Abstract</p> <p>Background</p> <p>Parkinson’s disease is a high incidence neurodegenerative disease in elderly people, and oxidative stress plays an important role in the pathogenesis. Oxygen metabolism in the brain is high, which lacks an antioxidative protection me...

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Bibliographic Details
Main Authors: Ye Qinyong, Ye Linfeng, Xu Xianjie, Huang Bixia, Zhang Xiaodong, Zhu Yuangui, Chen Xiaochun
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Parkinson’s disease
(−)-epigallocatechin-3-gallate
PC12 cells
PGC-1α
SIRT1
Online Access:http://www.biomedcentral.com/1472-6882/12/82

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