In vivo dynamics of AAV-mediated gene delivery to sensory neurons of the trigeminal ganglia

Abstract The ability to genetically manipulate trigeminal ganglion (TG) neurons would be useful in the study of the craniofacial nervous system and latent alphaherpesvirus infections. We investigated adeno-associated virus (AAV) vectors for gene delivery to the TG after intradermal whiskerpad delive...

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Bibliographic Details
Main Authors: Chung H. Dang, Martine Aubert, Harshana S. De Silva Feelixge, Kurt Diem, Michelle A. Loprieno, Pavitra Roychoudhury, Daniel Stone, Keith R. Jerome
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01004-y