Dopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson’s Disease Model

Dopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson’s Disease Model

Neural transplantation in neurodegenerative diseases such as Parkinson’s disease (PD) offers to replace cells lost during the progression of the disease process. Primary fetal ventral mesencephalon (VM), the origin of bona fide midbrain dopaminergic (DAergic) precursors, is currently the gold standa...

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Bibliographic Details
Main Authors: Sophie V. Precious, Gaynor A. Smith, Andreas Heuer, Ines Jaeger, Emma L. Lane, Stephen B. Dunnett, Meng Li, Claire M. Kelly, Anne E. Rosser
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neuroscience
Subjects:
transplantation
Parkinson’s disease
dopaminergic neurons
primary fetal ventral mesencephalon
stem cells
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00312/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00312/full

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