A novel discovery, maturation, and assay integration approach for the development of ruggedized multi-valent capture receptors exemplified against the chikungunya virus E2 protein

A novel discovery, maturation, and assay integration approach for the development of ruggedized multi-valent capture receptors exemplified against the chikungunya virus E2 protein

This work reports on the development of synthetic, thermally stable receptors using a novel discovery and multi-valent maturation strategy exemplified against the Chikungunya Virus (CHIKV) E2 surface protein capable of straightforward bioassay integration. An in situ ‘click’ screen of a propargylate...

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Bibliographic Details
Main Authors: Matthew B. Coppock, Margaret Hurley, Curtis Jones, Daniela Erickson, Dimitra N. Stratis-Cullum
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Sensing and Bio-Sensing Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2214180418300692

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http://www.sciencedirect.com/science/article/pii/S2214180418300692

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