Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes

Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes

Abstract Background Epigenetic regulators are frequently mutated or aberrantly expressed in a variety of cancers, leading to altered transcription states that result in changes in cell identity, behavior, and response to therapy. Results To define alterations in epigenetic landscapes in breast cance...

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Bibliographic Details
Main Authors: Yuanxin Xi, Jiejun Shi, Wenqian Li, Kaori Tanaka, Kendra L. Allton, Dana Richardson, Jing Li, Hector L. Franco, Anusha Nagari, Venkat S. Malladi, Luis Della Coletta, Melissa S. Simper, Khandan Keyomarsi, Jianjun Shen, Mark T. Bedford, Xiaobing Shi, Michelle C. Barton, W. Lee Kraus, Wei Li, Sharon Y. R. Dent
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Genomics
Subjects:
Breast cancer subtypes
Epigenetics
Histone modifications
Chromatin states
Online Access:http://link.springer.com/article/10.1186/s12864-018-4533-0

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