PDGF and FGF2 pathways regulate distinct oligodendrocyte lineage responses in experimental demyelination with spontaneous remyelination
Repair of myelin damage in the adult CNS requires oligodendrocyte progenitor (OP) proliferation and subsequent differentiation into remyelinating oligodendrocytes. Platelet-derived growth factor (PDGF) and fibroblast growth factor-2 (FGF2) have been predicted to act individually and/or cooperatively...
Main Authors: | Joshua C. Murtie, Yong-Xing Zhou, Tuan Q. Le, Adam C. Vana, Regina C. Armstrong |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2005-06-01
|
Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996104002918 |
Similar Items
-
Particles Containing Cells as a Strategy to Promote Remyelination in Patients With Multiple Sclerosis
by: Jorge Matías-Guiu, et al.
Published: (2020-07-01) -
Butyrate suppresses demyelination and enhances remyelination
by: Tong Chen, et al.
Published: (2019-08-01) -
Mechanisms of remyelination: recent insight from experimental models
by: Tanaka Tatsuhide, et al.
Published: (2014-08-01) -
A novel model of demyelination and remyelination in a GFP-transgenic zebrafish
by: Yangwu Fang, et al.
Published: (2014-12-01) -
Osteopontin is extensively expressed by macrophages following CNS demyelination but has a redundant role in remyelination
by: Chao Zhao, et al.
Published: (2008-08-01)