Unexpected relationships and inbreeding in HapMap phase III populations.
Correct annotation of the genetic relationships between samples is essential for population genomic studies, which could be biased by errors or omissions. To this end, we used identity-by-state (IBS) and identity-by-descent (IBD) methods to assess genetic relatedness of individuals within HapMap pha...
Main Authors: | Eric L Stevens, Joseph D Baugher, Matthew D Shirley, Laurence P Frelin, Jonathan Pevsner |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3501496?pdf=render |
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