Brugada Syndrome-Associated Genetic Loci Are Associated With J-Point Elevation and an Increased Risk of Cardiac Arrest

Introduction: A previous genome-wide association study found three genetic loci, rs9388451, rs10428132, and rs11708996, to increase the risk of Brugada Syndrome (BrS). Since the effect of these loci in the general population is unknown, we aimed to investigate the effect on electrocardiogram (ECG) p...

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Bibliographic Details
Main Authors: Laura Andreasen, Jonas Ghouse, Morten W. Skov, Christian T. Have, Gustav Ahlberg, Peter V. Rasmussen, Allan Linneberg, Oluf Pedersen, Pyotr G. Platonov, Stig Haunsø, Jesper H. Svendsen, Torben Hansen, Jørgen K. Kanters, Morten S. Olesen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00894/full