Association between Lifestyle Factors and Oral Potentially Malignant Disorders among People of Bangalore: A Case-control Study
Introduction: The increase in prevalence of oral premalignant lesions and oral cancer in India is due to cultural, ethnic, geographic factors and varying lifestyle factors like consumption of tobacco, alcohol and standard of living. Some of the risk factors are modifiable and emphasises the need...
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doaj-b6d61214227b4b0899029790e40a1c612021-06-18T07:15:52ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-03-01153ZC27ZC3110.7860/JCDR/2021/46125.14649Association between Lifestyle Factors and Oral Potentially Malignant Disorders among People of Bangalore: A Case-control StudyJyoti Raghavendra Byakodi0Pushpanjali Krishnappa1Reader, Department of Public Health Dentistry, Vasantdada Patil Dental College and Hospital, Sangli, Maharashtra, India.Professor and Head, Department of Public Health Dentistry, M S Ramaiah Dental College and Hospital, Bangalore, Karnataka, India.Introduction: The increase in prevalence of oral premalignant lesions and oral cancer in India is due to cultural, ethnic, geographic factors and varying lifestyle factors like consumption of tobacco, alcohol and standard of living. Some of the risk factors are modifiable and emphasises the need for detailed assessment of these modifiable risk factors and increasing awareness among general public and policy makers. Aim: The present study was conducted to assess the association between lifestyle factors and Oral Potentially Malignant Disorders (OPMDs). Materials and Methods: A case-control study was conducted where 154 cases and controls were selected from MS Ramaiah Dental College and Hospital, Bangalore and peripheral outreach centers of MS Ramaiah Dental College and Hospital, Bangalore. Cases diagnosed as oral leukoplakia, erythroplakia and Oral Submucous Fibrosis (OSMF) based on the World Health Organisation (WHO) criteria (1980) were included in the study group. Age and sex (1:1) matched controls without OPMDs were included in control group. The data was collected regarding socio-demographic factors, blood group and lifestyle factors using specially designed proforma. Chisquare test and odds ratio were utilised to association and strength of association between various lifestyle factors and development of OPMDs. Univariate logistic regression test was done followed by multiple logistic regression for identifying the risk factors. The p-value <0.05 was considered as statistically significant. SPSS version 11.0 was used for data analysis. Results: Out of 154 cases, 84 (54.5%) cases were leukoplakia, 2 (1.3%), cases were erythroplakia, 53 (34.4%) cases were OSMF and 15 (9.7%) cases were with multiple potentially malignant disorders (leukoplakia+OSMF). In univariate analysis, OR for tobacco smoking in individuals who smoked more than 20 times a day was 2.56 (95% CL 1.19-5.5) compared to nonsmokers, tobacco chewing who chewed more than 10 times a day was 43.03 (95% CL-17.2-107) in comparison to nonchewers and alcohol consumption who consumed alcohol daily was 3.2 (95% CL 0.6-16.3) in comparison to non-alcoholics. Following multiple logistic regression analysis occupation, smoking, chewing tobacco and vegetable intake was found to be statistically significant as independent risk factors p<0.05. Conclusion: Occupation, smoking, chewing tobacco and vegetable consumption were identified as independent risk factors for the development of OPMDs. Identifying the risk factors and OPMD at an early stage is important for prevention of oral cancer.https://www.jcdr.net/articles/PDF/14649/46125_CE[Ra1]_F[SK]_PF1(ShG_KM)_PFA(SHU_ShG)_PN(KM).pdfalcohol consumptiondietfruits-vegetables intakeleukoplakiaoral mucosal lesionsoral submucous fibrosisrisk factorssmokingtobacco |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Jyoti Raghavendra Byakodi Pushpanjali Krishnappa |
spellingShingle |
Jyoti Raghavendra Byakodi Pushpanjali Krishnappa Association between Lifestyle Factors and Oral Potentially Malignant Disorders among People of Bangalore: A Case-control Study Journal of Clinical and Diagnostic Research alcohol consumption diet fruits-vegetables intake leukoplakia oral mucosal lesions oral submucous fibrosis risk factors smoking tobacco |
author_facet |
Jyoti Raghavendra Byakodi Pushpanjali Krishnappa |
author_sort |
Jyoti Raghavendra Byakodi |
title |
Association between Lifestyle Factors and Oral Potentially Malignant Disorders among People of Bangalore: A Case-control Study |
title_short |
Association between Lifestyle Factors and Oral Potentially Malignant Disorders among People of Bangalore: A Case-control Study |
title_full |
Association between Lifestyle Factors and Oral Potentially Malignant Disorders among People of Bangalore: A Case-control Study |
title_fullStr |
Association between Lifestyle Factors and Oral Potentially Malignant Disorders among People of Bangalore: A Case-control Study |
title_full_unstemmed |
Association between Lifestyle Factors and Oral Potentially Malignant Disorders among People of Bangalore: A Case-control Study |
title_sort |
association between lifestyle factors and oral potentially malignant disorders among people of bangalore: a case-control study |
publisher |
JCDR Research and Publications Private Limited |
series |
Journal of Clinical and Diagnostic Research |
issn |
2249-782X 0973-709X |
publishDate |
2021-03-01 |
description |
Introduction: The increase in prevalence of oral premalignant
lesions and oral cancer in India is due to cultural, ethnic,
geographic factors and varying lifestyle factors like consumption
of tobacco, alcohol and standard of living. Some of the risk
factors are modifiable and emphasises the need for detailed
assessment of these modifiable risk factors and increasing
awareness among general public and policy makers.
Aim: The present study was conducted to assess the association
between lifestyle factors and Oral Potentially Malignant Disorders
(OPMDs).
Materials and Methods: A case-control study was conducted
where 154 cases and controls were selected from MS Ramaiah
Dental College and Hospital, Bangalore and peripheral
outreach centers of MS Ramaiah Dental College and Hospital,
Bangalore. Cases diagnosed as oral leukoplakia, erythroplakia
and Oral Submucous Fibrosis (OSMF) based on the World
Health Organisation (WHO) criteria (1980) were included
in the study group. Age and sex (1:1) matched controls
without OPMDs were included in control group. The data was
collected regarding socio-demographic factors, blood group
and lifestyle factors using specially designed proforma. Chisquare test and odds ratio were utilised to association and
strength of association between various lifestyle factors and
development of OPMDs. Univariate logistic regression test was
done followed by multiple logistic regression for identifying the
risk factors. The p-value <0.05 was considered as statistically
significant. SPSS version 11.0 was used for data analysis.
Results: Out of 154 cases, 84 (54.5%) cases were leukoplakia,
2 (1.3%), cases were erythroplakia, 53 (34.4%) cases were
OSMF and 15 (9.7%) cases were with multiple potentially
malignant disorders (leukoplakia+OSMF). In univariate analysis,
OR for tobacco smoking in individuals who smoked more than
20 times a day was 2.56 (95% CL 1.19-5.5) compared to nonsmokers, tobacco chewing who chewed more than 10 times
a day was 43.03 (95% CL-17.2-107) in comparison to nonchewers and alcohol consumption who consumed alcohol daily
was 3.2 (95% CL 0.6-16.3) in comparison to non-alcoholics.
Following multiple logistic regression analysis occupation,
smoking, chewing tobacco and vegetable intake was found to
be statistically significant as independent risk factors p<0.05.
Conclusion: Occupation, smoking, chewing tobacco and
vegetable consumption were identified as independent risk
factors for the development of OPMDs. Identifying the risk
factors and OPMD at an early stage is important for prevention
of oral cancer. |
topic |
alcohol consumption diet fruits-vegetables intake leukoplakia oral mucosal lesions oral submucous fibrosis risk factors smoking tobacco |
url |
https://www.jcdr.net/articles/PDF/14649/46125_CE[Ra1]_F[SK]_PF1(ShG_KM)_PFA(SHU_ShG)_PN(KM).pdf |
work_keys_str_mv |
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