Ecology-guided prediction of cross-feeding interactions in the human gut microbiome

Understanding a complex microbial ecosystem such as the human gut microbiome requires information about both microbial species and the metabolites they produce and secrete. Here, the authors propose an ecology-based computational method to predict hundreds of new experimentally untested cross-feedin...

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Main Authors: Akshit Goyal, Tong Wang, Veronika Dubinkina, Sergei Maslov
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21586-6
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spelling doaj-b6e3f2f488c24fc98ae27509782db76e2021-03-11T11:31:32ZengNature Publishing GroupNature Communications2041-17232021-02-0112111010.1038/s41467-021-21586-6Ecology-guided prediction of cross-feeding interactions in the human gut microbiomeAkshit Goyal0Tong Wang1Veronika Dubinkina2Sergei Maslov3Physics of Living Systems, Department of Physics, Massachusetts Institute of TechnologyDepartment of Physics, University of Illinois at Urbana-ChampaignDepartment of Bioengineering and Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-ChampaignDepartment of Physics, University of Illinois at Urbana-ChampaignUnderstanding a complex microbial ecosystem such as the human gut microbiome requires information about both microbial species and the metabolites they produce and secrete. Here, the authors propose an ecology-based computational method to predict hundreds of new experimentally untested cross-feeding interactions in the human gut microbiome.https://doi.org/10.1038/s41467-021-21586-6
collection DOAJ
language English
format Article
sources DOAJ
author Akshit Goyal
Tong Wang
Veronika Dubinkina
Sergei Maslov
spellingShingle Akshit Goyal
Tong Wang
Veronika Dubinkina
Sergei Maslov
Ecology-guided prediction of cross-feeding interactions in the human gut microbiome
Nature Communications
author_facet Akshit Goyal
Tong Wang
Veronika Dubinkina
Sergei Maslov
author_sort Akshit Goyal
title Ecology-guided prediction of cross-feeding interactions in the human gut microbiome
title_short Ecology-guided prediction of cross-feeding interactions in the human gut microbiome
title_full Ecology-guided prediction of cross-feeding interactions in the human gut microbiome
title_fullStr Ecology-guided prediction of cross-feeding interactions in the human gut microbiome
title_full_unstemmed Ecology-guided prediction of cross-feeding interactions in the human gut microbiome
title_sort ecology-guided prediction of cross-feeding interactions in the human gut microbiome
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-02-01
description Understanding a complex microbial ecosystem such as the human gut microbiome requires information about both microbial species and the metabolites they produce and secrete. Here, the authors propose an ecology-based computational method to predict hundreds of new experimentally untested cross-feeding interactions in the human gut microbiome.
url https://doi.org/10.1038/s41467-021-21586-6
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