Somatic mutation of DNAH genes implicated higher chemotherapy response rate in gastric adenocarcinoma patients

Somatic mutation of DNAH genes implicated higher chemotherapy response rate in gastric adenocarcinoma patients

Abstract Background The dynein axonemal heavy chain (DNAH) family of genes encode the dynein axonemal heavy chain, which is involved in cell motility. Genomic variations of DNAH family members have been frequently reported in diverse kinds of malignant tumors. In this study, we analyzed the genomic...

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Bibliographic Details
Main Authors: Chunchao Zhu, Qin Yang, Jia Xu, Wenyi Zhao, Zizhen Zhang, Danhua Xu, Yeqian Zhang, Enhao Zhao, Gang Zhao
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Journal of Translational Medicine
Subjects:
Gastric cancer
DNAH mutation
TCGA
Chemotherapy response
Online Access:http://link.springer.com/article/10.1186/s12967-019-1867-6

Internet

http://link.springer.com/article/10.1186/s12967-019-1867-6

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