Benchmarking the Human Leukocyte Antigen Typing Performance of Three Assays and Seven Next-Generation Sequencing-Based Algorithms

Benchmarking the Human Leukocyte Antigen Typing Performance of Three Assays and Seven Next-Generation Sequencing-Based Algorithms

With the great progress made recently in next generation sequencing (NGS) technology, sequencing accuracy and throughput have increased, while the cost for data has decreased. Various human leukocyte antigen (HLA) typing algorithms and assays have been developed and have begun to be used in clinical...

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Bibliographic Details
Main Authors: Ping Liu, Minya Yao, Yu Gong, Yunjie Song, Yanan Chen, Yizhou Ye, Xiao Liu, Fugen Li, Hua Dong, Rui Meng, Hao Chen, Aiwen Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
human leukocyte antigen
accuracy
next-generation sequencing
algorithms
benchmark
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.652258/full

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