Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species

Spleen Tyrosine Kinase Is a Critical Regulator of Neutrophil Responses to Candida Species

Neutrophils are recognized to represent significant immune cell mediators for the clearance and elimination of the human-pathogenic fungal pathogen Candida. The sensing of fungi by innate cells is performed, in part, through lectin receptor recognition of cell wall components and downstream cellular...

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Bibliographic Details
Main Authors: Paige E. Negoro, Shuying Xu, Zeina Dagher, Alex Hopke, Jennifer L. Reedy, Michael B. Feldman, Nida S. Khan, Adam L. Viens, Natalie J. Alexander, Natalie J. Atallah, Allison K. Scherer, Richard A. Dutko, Jane Jeffery, John F. Kernien, J. Scott Fites, Jeniel E. Nett, Bruce S. Klein, Jatin M. Vyas, Daniel Irimia, David B. Sykes, Michael K. Mansour
Format: Article
Language:English
Published: American Society for Microbiology 2020-05-01
Series:mBio
Subjects:
neutrophils
spleen tyrosine kinase
candida
fungus
Online Access:https://doi.org/10.1128/mBio.02043-19

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