Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome
The hypothesis that the most common female endocrine disease, the polycystic ovarian syndrome (PCOS), has a male equivalent, has recently become more widely accepted. The male form of PCOS is marked by alterations in the secretion of gonadotropins, increased insulin resistance, and changes of the le...
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Karolinum Press
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Online Access: | https://pmr.lf1.cuni.cz/122/2/0073/ |
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doaj-b713809a976241b99a41a7355e44d6552021-06-22T08:56:05ZengKarolinum PressPrague Medical Report1214-69942336-29362021-06-011222737910.14712/23362936.2021.811447Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary SyndromeLuboslav StárkaMichaela DuškováThe hypothesis that the most common female endocrine disease, the polycystic ovarian syndrome (PCOS), has a male equivalent, has recently become more widely accepted. The male form of PCOS is marked by alterations in the secretion of gonadotropins, increased insulin resistance, and changes of the levels of several steroid hormones, with clinical manifestations including premature androgenic alopecia (AGA). Because these symptoms are not always found in men with genetic predispositions, knowledge of the male equivalent of PCOS needs to be supplemented by measurements of adrenal 11-oxygenated C19 steroids, particularly 11-keto-, and 11β-hydroxy-derivatives of testosterone and dihydrotestosterone, by focusing on the newly-realized role of skin as an endocrine organ, and by confirming any age-related factors in glucose metabolism disorders in such predisposed men.https://pmr.lf1.cuni.cz/122/2/0073/polycystic ovarian syndromepremature androgenic alopeciaandrogensshbginsulin resistance |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Luboslav Stárka Michaela Dušková |
spellingShingle |
Luboslav Stárka Michaela Dušková Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome Prague Medical Report polycystic ovarian syndrome premature androgenic alopecia androgens shbg insulin resistance |
author_facet |
Luboslav Stárka Michaela Dušková |
author_sort |
Luboslav Stárka |
title |
Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome |
title_short |
Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome |
title_full |
Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome |
title_fullStr |
Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome |
title_full_unstemmed |
Remarks on the Hormonal Background of the Male Equivalent of Polycystic Ovary Syndrome |
title_sort |
remarks on the hormonal background of the male equivalent of polycystic ovary syndrome |
publisher |
Karolinum Press |
series |
Prague Medical Report |
issn |
1214-6994 2336-2936 |
publishDate |
2021-06-01 |
description |
The hypothesis that the most common female endocrine disease, the polycystic ovarian syndrome (PCOS), has a male equivalent, has recently become more widely accepted. The male form of PCOS is marked by alterations in the secretion of gonadotropins, increased insulin resistance, and changes of the levels of several steroid hormones, with clinical manifestations including premature androgenic alopecia (AGA). Because these symptoms are not always found in men with genetic predispositions, knowledge of the male equivalent of PCOS needs to be supplemented by measurements of adrenal 11-oxygenated C19 steroids, particularly 11-keto-, and 11β-hydroxy-derivatives of testosterone and dihydrotestosterone, by focusing on the newly-realized role of skin as an endocrine organ, and by confirming any age-related factors in glucose metabolism disorders in such predisposed men. |
topic |
polycystic ovarian syndrome premature androgenic alopecia androgens shbg insulin resistance |
url |
https://pmr.lf1.cuni.cz/122/2/0073/ |
work_keys_str_mv |
AT luboslavstarka remarksonthehormonalbackgroundofthemaleequivalentofpolycysticovarysyndrome AT michaeladuskova remarksonthehormonalbackgroundofthemaleequivalentofpolycysticovarysyndrome |
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1721363510597779456 |