Evaluation of the effectiveness of treatment of experimental postoperative peritonitis

• Main Author: M. M. Droniak
• Format: Article
• Language: English
• Published: Kazimierz Wielki University 2021-01-01
• Series: Journal of Education, Health and Sport
• Subjects: postoperative peritonitis; experiment; sanitation of the abdominal cavity
• Online Access: https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/34271

<p><strong>Purpose:</strong> to develop a new method of lavage of the abdominal cavity in the experimental conditions.</p><p><strong>Materials and methods.</strong> In the experiment we use 40 rats Wistar line weighing 160-240 g, kept in a vivarium in compliance with all standards.</p><p><strong>Research results and their discussion.</strong> During relaparotomy, we performed mechanical cleaning of the abdominal cavity from fecal masses, layers of fibrin, the abdominal cavity was washed twice with 100 ml of 0.02% decamethoxine solution at a temperature of 30-35 ° C. After removing the drug residues from the abdominal cavity, we pour 50 ml of Extranil peritoneal dialysis solution at a temperature of370C, the active substance of which is icodextrin, not glucose, ie it is not a nutrient medium for microorganisms, but has antimicrobial action due to hyperosmolarity and increases its adsorption properties.</p>