A comprehensive model of the spatio-temporal stem cell and tissue organisation in the intestinal crypt.
We introduce a novel dynamic model of stem cell and tissue organisation in murine intestinal crypts. Integrating the molecular, cellular and tissue level of description, this model links a broad spectrum of experimental observations encompassing spatially confined cell proliferation, directed cell m...
Main Authors: | Peter Buske, Jörg Galle, Nick Barker, Gabriela Aust, Hans Clevers, Markus Loeffler |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3017108?pdf=render |
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