Goose skin in a girl with Ehlers–Danlos syndrome

• Main Authors: Jared Martínez-Coronado, Bertha Torres-Alvarez, Juan Pablo Castanedo-Cázares
• Format: Article
• Language: English
• Published: Taylor & Francis Group 2015-09-01
• Series: Journal of Community Hospital Internal Medicine Perspectives
• Subjects: pellagra; Ehlers–Danlos syndrome; nicotinamide; goose skin
• Online Access: http://www.jchimp.net/index.php/jchimp/article/view/28216/pdf_84

Pellagra is a nutritional disorder secondary to niacin deficiency. The classical triad is dermatitis, diarrhea, and dementia. We report the case of a young girl with hypermobility-type Ehlers–Danlos syndrome who exhibited the classical pellagra symptoms, despite apparent adequate nutritional intake. Her condition resolved after oral niacin supplements were administered. Although this association has not previously been recognized, an inherited connective tissue disorder may be related to the appearance of pellagra.