Is HIV a Risk Factor for Adverse In-Hospital Cardiovascular Events Following Noncardiac Surgery?

Background: It is unknown whether HIV infection is a risk factor for adverse in-hospital cardiovascular events (AICEs) following noncardiac surgery. We conducted an unmatched case-control analysis of adult noncardiac surgery patient data from the 2009-2011 California State Inpatient Database (SID) t...

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Bibliographic Details
Main Author: Yoshan Moodley
Format: Article
Language:English
Published: Light House Polyclinic Mangalore 2017-01-01
Series:Online Journal of Health & Allied Sciences
Subjects:
HIV
Online Access:http://www.ojhas.org/issue60/2016-4-4.html
Description
Summary:Background: It is unknown whether HIV infection is a risk factor for adverse in-hospital cardiovascular events (AICEs) following noncardiac surgery. We conducted an unmatched case-control analysis of adult noncardiac surgery patient data from the 2009-2011 California State Inpatient Database (SID) to address this question. Methods: HIV status, established risk factors, and AICEs were determined for each eligible patient in the SID. The final analysis involved 1145 patients who suffered an AICE (cases), and 2290 patients who did not suffer an AICE (controls). Data were analysed using univariate (Mann-Whitney U test, χ2 and Fisher’s Exact Test) and multivariate (binary logistic regression) statistical methods. Results: HIV infection was not an independent predictor of AICEs in this study (Odds Ratio: 2.711, 95% Confidence Interval: 0.874-8.405; p=0.084). Conclusion: Further research is required to determine whether HIV infection, particularly that which is poorly controlled, is associated with a higher risk of AICEs following noncardiac surgery.
ISSN:0972-5997
0972-5997