Efficacy and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules
Objective : To study the effectiveness and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules. Materials and Methods : USG of the thyroid gland was performed in 54 patients suspected to have a thyroid nodule on clinical examination. All patients with a predominantly cystic nodule...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2009-07-01
|
Series: | Indian Journal of Radiology and Imaging |
Subjects: | |
Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.54879 |
id |
doaj-b7422c4636864fc4a9d63e6ed122dc5b |
---|---|
record_format |
Article |
spelling |
doaj-b7422c4636864fc4a9d63e6ed122dc5b2021-08-02T23:34:19ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Radiology and Imaging0971-30261998-38082009-07-01190319920210.4103/0971-3026.54879Efficacy and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodulesSR Jayesh0Pankaj Mehta1Mathew P Cherian2V Ilayaraja3Prashanth Gupta4K Venkatesh5Department of Radiology, Kovai Medical Center and Hospital, Avinashi Road, Coimbatore, Tamil Nadu, IndiaDepartment of Radiology, Kovai Medical Center and Hospital, Avinashi Road, Coimbatore, Tamil Nadu, IndiaDepartment of Radiology, Kovai Medical Center and Hospital, Avinashi Road, Coimbatore, Tamil Nadu, IndiaDepartment of Radiology, Kovai Medical Center and Hospital, Avinashi Road, Coimbatore, Tamil Nadu, IndiaDepartment of Radiology, Kovai Medical Center and Hospital, Avinashi Road, Coimbatore, Tamil Nadu, IndiaDepartment of Radiology, Kovai Medical Center and Hospital, Avinashi Road, Coimbatore, Tamil Nadu, IndiaObjective : To study the effectiveness and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules. Materials and Methods : USG of the thyroid gland was performed in 54 patients suspected to have a thyroid nodule on clinical examination. All patients with a predominantly cystic nodule (i.e., when >2/3 rd of the nodule was cystic) were included in the study. Ethanol was injected into the cyst under USG guidance. The amount of ethanol injected was about 50% of the amount of aspirated fluid. Follow-up USG was done every month for 3 months; ethanol was re-injected when there was no significant reduction in the cyst volume. The initial cyst volume was compared with the final volume; statistical significance was assessed using the paired t-test. Results : USG revealed predominant cystic nodules in 16 of the 54 patients. Fifteen patients were selected for the study. Following ethanol sclerotherapy, four out of the 15 patients (26.6%) showed complete disappearance of the cyst and nine (60%) showed significant reduction in the cyst volume (i.e., reduction of cyst volume by ≥50% of initial volume). Only two patients did not show significant reduction in cyst volume; both these patients had nodules with an initial volume of ≥20 cc. There were no complications attributable to ethanol injection during follow-up. Conclusion: Ethanol sclerotherapy is an effective and safe treatment for benign cystic thyroid nodules with volumes of < 20 cc. Cystic nodules with volume >20 cc may need more number of alcohol injections and longer follow-up.http://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.54879cystic thyroid nodulesethanol sclerotherapy |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
SR Jayesh Pankaj Mehta Mathew P Cherian V Ilayaraja Prashanth Gupta K Venkatesh |
spellingShingle |
SR Jayesh Pankaj Mehta Mathew P Cherian V Ilayaraja Prashanth Gupta K Venkatesh Efficacy and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules Indian Journal of Radiology and Imaging cystic thyroid nodules ethanol sclerotherapy |
author_facet |
SR Jayesh Pankaj Mehta Mathew P Cherian V Ilayaraja Prashanth Gupta K Venkatesh |
author_sort |
SR Jayesh |
title |
Efficacy and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules |
title_short |
Efficacy and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules |
title_full |
Efficacy and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules |
title_fullStr |
Efficacy and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules |
title_full_unstemmed |
Efficacy and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules |
title_sort |
efficacy and safety of usg-guided ethanol sclerotherapy in cystic thyroid nodules |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
series |
Indian Journal of Radiology and Imaging |
issn |
0971-3026 1998-3808 |
publishDate |
2009-07-01 |
description |
Objective : To study the effectiveness and safety of USG-guided ethanol sclerotherapy in cystic thyroid nodules. Materials and Methods : USG of the thyroid gland was performed in 54 patients suspected to have a thyroid nodule on clinical examination. All patients with a predominantly cystic nodule (i.e., when >2/3 rd of the nodule was cystic) were included in the study. Ethanol was injected into the cyst under USG guidance. The amount of ethanol injected was about 50% of the amount of aspirated fluid. Follow-up USG was done every month for 3 months; ethanol was re-injected when there was no significant reduction in the cyst volume. The initial cyst volume was compared with the final volume; statistical significance was assessed using the paired t-test. Results : USG revealed predominant cystic nodules in 16 of the 54 patients. Fifteen patients were selected for the study. Following ethanol sclerotherapy, four out of the 15 patients (26.6%) showed complete disappearance of the cyst and nine (60%) showed significant reduction in the cyst volume (i.e., reduction of cyst volume by ≥50% of initial volume). Only two patients did not show significant reduction in cyst volume; both these patients had nodules with an initial volume of ≥20 cc. There were no complications attributable to ethanol injection during follow-up. Conclusion: Ethanol sclerotherapy is an effective and safe treatment for benign cystic thyroid nodules with volumes of < 20 cc. Cystic nodules with volume >20 cc may need more number of alcohol injections and longer follow-up. |
topic |
cystic thyroid nodules ethanol sclerotherapy |
url |
http://www.thieme-connect.de/DOI/DOI?10.4103/0971-3026.54879 |
work_keys_str_mv |
AT srjayesh efficacyandsafetyofusgguidedethanolsclerotherapyincysticthyroidnodules AT pankajmehta efficacyandsafetyofusgguidedethanolsclerotherapyincysticthyroidnodules AT mathewpcherian efficacyandsafetyofusgguidedethanolsclerotherapyincysticthyroidnodules AT vilayaraja efficacyandsafetyofusgguidedethanolsclerotherapyincysticthyroidnodules AT prashanthgupta efficacyandsafetyofusgguidedethanolsclerotherapyincysticthyroidnodules AT kvenkatesh efficacyandsafetyofusgguidedethanolsclerotherapyincysticthyroidnodules |
_version_ |
1721225551435268096 |