Strongyloides stercoralis and Organ Transplantation

Strongyloides is a parasite that is common in tropical regions. Infection in the immunocompetent host is usually associated with mild gastrointestinal symptoms. However, in immunosuppressed individuals it has been known to cause a “hyperinfection syndrome” with fatal complications. Reactivation of l...

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Main Authors: Bhalaghuru Chokkalingam Mani, Moses Mathur, Heather Clauss, Rene Alvarez, Eman Hamad, Yoshiya Toyoda, Mark Birkenbach, Mustafa Ahmed
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2013/549038
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spelling doaj-b7572b5e5b9f4f688288b67b8c9f7e302020-11-24T23:20:22ZengHindawi LimitedCase Reports in Transplantation2090-69432090-69512013-01-01201310.1155/2013/549038549038Strongyloides stercoralis and Organ TransplantationBhalaghuru Chokkalingam Mani0Moses Mathur1Heather Clauss2Rene Alvarez3Eman Hamad4Yoshiya Toyoda5Mark Birkenbach6Mustafa Ahmed7Section of Cardiology, Temple University School of Medicine, Philadelphia, PA 19140, USASection of Cardiology, Temple University School of Medicine, Philadelphia, PA 19140, USASection of Infectious Diseases, Temple University School of Medicine, Philadelphia, PA 19140, USASection of Cardiology, Temple University School of Medicine, Philadelphia, PA 19140, USASection of Cardiology, Temple University School of Medicine, Philadelphia, PA 19140, USASection of Cardiothoracic Surgery, Temple University School of Medicine, Philadelphia, PA 19140, USADepartment of Pathology, Temple University School of Medicine, Philadelphia, PA 19140, USASection of Cardiology, Temple University School of Medicine, Philadelphia, PA 19140, USAStrongyloides is a parasite that is common in tropical regions. Infection in the immunocompetent host is usually associated with mild gastrointestinal symptoms. However, in immunosuppressed individuals it has been known to cause a “hyperinfection syndrome” with fatal complications. Reactivation of latent infection and rarely transmission from donor organs in transplanted patients have been suggested as possible causes. Our case highlights the importance suspecting Strongyloides in transplant recipients with atypical presentations and demonstrates an incidence of donor derived infection. We also review the challenges associated with making this diagnosis.http://dx.doi.org/10.1155/2013/549038
collection DOAJ
language English
format Article
sources DOAJ
author Bhalaghuru Chokkalingam Mani
Moses Mathur
Heather Clauss
Rene Alvarez
Eman Hamad
Yoshiya Toyoda
Mark Birkenbach
Mustafa Ahmed
spellingShingle Bhalaghuru Chokkalingam Mani
Moses Mathur
Heather Clauss
Rene Alvarez
Eman Hamad
Yoshiya Toyoda
Mark Birkenbach
Mustafa Ahmed
Strongyloides stercoralis and Organ Transplantation
Case Reports in Transplantation
author_facet Bhalaghuru Chokkalingam Mani
Moses Mathur
Heather Clauss
Rene Alvarez
Eman Hamad
Yoshiya Toyoda
Mark Birkenbach
Mustafa Ahmed
author_sort Bhalaghuru Chokkalingam Mani
title Strongyloides stercoralis and Organ Transplantation
title_short Strongyloides stercoralis and Organ Transplantation
title_full Strongyloides stercoralis and Organ Transplantation
title_fullStr Strongyloides stercoralis and Organ Transplantation
title_full_unstemmed Strongyloides stercoralis and Organ Transplantation
title_sort strongyloides stercoralis and organ transplantation
publisher Hindawi Limited
series Case Reports in Transplantation
issn 2090-6943
2090-6951
publishDate 2013-01-01
description Strongyloides is a parasite that is common in tropical regions. Infection in the immunocompetent host is usually associated with mild gastrointestinal symptoms. However, in immunosuppressed individuals it has been known to cause a “hyperinfection syndrome” with fatal complications. Reactivation of latent infection and rarely transmission from donor organs in transplanted patients have been suggested as possible causes. Our case highlights the importance suspecting Strongyloides in transplant recipients with atypical presentations and demonstrates an incidence of donor derived infection. We also review the challenges associated with making this diagnosis.
url http://dx.doi.org/10.1155/2013/549038
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