Sotetsuflavone Induces Autophagy in Non-Small Cell Lung Cancer Through Blocking PI3K/Akt/mTOR Signaling Pathway in Vivo and in Vitro

Sotetsuflavone Induces Autophagy in Non-Small Cell Lung Cancer Through Blocking PI3K/Akt/mTOR Signaling Pathway in Vivo and in Vitro

Non-small cell lung cancer (NSCLC) is a globally scaled disease with a high incidence and high associated mortality rate. Autophagy is one of the important physiological activities that helps to control cell survival, influences the dynamics of cell death, and which plays a crucial role in the patho...

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Bibliographic Details
Main Authors: Shaohui Wang, Xiaoling Xu, Yanlan Hu, Tao Lei, Tongxiang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Pharmacology
Subjects:
sotetsuflavone
non-small cell lung cancer
apoptosis
autophagy
PI3K/Akt/mTOR signaling pathway
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01460/full

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