Variation of Mycobacterium tuberculosis antigen-specific IFN-γ and IL-17 responses in healthy tuberculin skin test (TST)-positive human subjects.
To determine the variation of IFN-γ and IL-17 responses to M. tuberculosis antigens in healthy TST+ humans.We isolated peripheral blood mononuclear cells from 21 TST+ healthy adults, stimulated them with phytohemagglutinin (PHA), PPD, Ag85B, ESAT-6, and live M. bovis BCG, and assayed IFN-γ and IL-17...
Main Authors: | Lin Fan, He-Ping Xiao, Zhong-Yi Hu, Joel D Ernst |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3412824?pdf=render |
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