Practical synthesis of 5-hydroxy-2(5H)-furanone from furan

Practical synthesis of 5-hydroxy-2(5H)-furanone from furan

A simple, efficient and scalable method for the synthesis of 5-hydroxy-2(5H)-furanone from furan has been developed on a multigram scale. Oxidation of furan has been performed using oxone as the sole oxidant and water as a solvent, which makes this protocol practical and thus industrially applicable...

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Bibliographic Details
Main Authors: Subhash P. Chavan, Appasaheb L. Kadam
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Results in Chemistry
Subjects:
5-Hydroxy-2(5H)-furanone
Furan oxidation
On-water reaction
Oxone
Scalable synthesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715621000758
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spelling doaj-b78eb49262d04b42b76e38b0a6338f8a2021-08-14T04:30:28ZengElsevierResults in Chemistry2211-71562021-01-013100170Practical synthesis of 5-hydroxy-2(5H)-furanone from furanSubhash P. Chavan0Appasaheb L. Kadam1Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune 411008, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110025, India; Corresponding author.Division of Organic Chemistry, CSIR-National Chemical Laboratory, Pune 411008, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110025, IndiaA simple, efficient and scalable method for the synthesis of 5-hydroxy-2(5H)-furanone from furan has been developed on a multigram scale. Oxidation of furan has been performed using oxone as the sole oxidant and water as a solvent, which makes this protocol practical and thus industrially applicable.http://www.sciencedirect.com/science/article/pii/S22117156210007585-Hydroxy-2(5H)-furanoneFuran oxidationOn-water reactionOxoneScalable synthesis
collection DOAJ
language English
format Article
sources DOAJ
author Subhash P. Chavan
Appasaheb L. Kadam
spellingShingle Subhash P. Chavan
Appasaheb L. Kadam
Practical synthesis of 5-hydroxy-2(5H)-furanone from furan
Results in Chemistry
5-Hydroxy-2(5H)-furanone
Furan oxidation
On-water reaction
Oxone
Scalable synthesis
author_facet Subhash P. Chavan
Appasaheb L. Kadam
author_sort Subhash P. Chavan
title Practical synthesis of 5-hydroxy-2(5H)-furanone from furan
title_short Practical synthesis of 5-hydroxy-2(5H)-furanone from furan
title_full Practical synthesis of 5-hydroxy-2(5H)-furanone from furan
title_fullStr Practical synthesis of 5-hydroxy-2(5H)-furanone from furan
title_full_unstemmed Practical synthesis of 5-hydroxy-2(5H)-furanone from furan
title_sort practical synthesis of 5-hydroxy-2(5h)-furanone from furan
publisher Elsevier
series Results in Chemistry
issn 2211-7156
publishDate 2021-01-01
description A simple, efficient and scalable method for the synthesis of 5-hydroxy-2(5H)-furanone from furan has been developed on a multigram scale. Oxidation of furan has been performed using oxone as the sole oxidant and water as a solvent, which makes this protocol practical and thus industrially applicable.
topic 5-Hydroxy-2(5H)-furanone
Furan oxidation
On-water reaction
Oxone
Scalable synthesis
url http://www.sciencedirect.com/science/article/pii/S2211715621000758
work_keys_str_mv AT subhashpchavan practicalsynthesisof5hydroxy25hfuranonefromfuran
AT appasaheblkadam practicalsynthesisof5hydroxy25hfuranonefromfuran
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