Pregnancy-induced alterations in mitochondrial function in euthyroid pregnant women and pregnant women with subclinical hypothyroidism; relation to adverse outcome

Pregnancy-induced alterations in mitochondrial function in euthyroid pregnant women and pregnant women with subclinical hypothyroidism; relation to adverse outcome

Background: It is well documented that overt hypothyroidism is associated with adverse pregnancy outcomes, but studies of subclinical hypothyroidism have demonstrated conflicting results. Objective: Thyroid hormones are known to regulate mitochondrial function, and the aim of this study was to exami...

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Bibliographic Details
Main Authors: Anne-Dorthe Feldthusen, MD, Jacob Larsen, MSc, PhD, Palle L. Pedersen, MSc, PhD, Tina Toft Kristensen, MD, Jan Kvetny, MD, DMSc
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Journal of Clinical & Translational Endocrinology
Subjects:
Subclinical hypothyroidism
Pregnancy outcome
Mitochondrial dysfunction
Mitochondrial membrane potential
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2214623713000057

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