The Orphan Nuclear Receptor ERRγ Regulates Hepatic CB1 Receptor-Mediated Fibroblast Growth Factor 21 Gene Expression.

The Orphan Nuclear Receptor ERRγ Regulates Hepatic CB1 Receptor-Mediated Fibroblast Growth Factor 21 Gene Expression.

Fibroblast growth factor 21 (FGF21), a stress inducible hepatokine, is synthesized in the liver and plays important roles in glucose and lipid metabolism. However, the mechanism of hepatic cannabinoid type 1 (CB1) receptor-mediated induction of FGF21 gene expression is largely unknown.Activation of...

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Bibliographic Details
Main Authors: Yoon Seok Jung, Ji-Min Lee, Don-Kyu Kim, Yong-Soo Lee, Ki-Sun Kim, Yong-Hoon Kim, Jina Kim, Myung-Shik Lee, In-Kyu Lee, Seong Heon Kim, Sung Jin Cho, Won-Il Jeong, Chul-Ho Lee, Robert A Harris, Hueng-Sik Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4959684?pdf=render

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http://europepmc.org/articles/PMC4959684?pdf=render

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