The Gut Microbiota as a Therapeutic Target in IBD and Metabolic Disease: A Role for the Bile Acid Receptors FXR and TGR5

The Gut Microbiota as a Therapeutic Target in IBD and Metabolic Disease: A Role for the Bile Acid Receptors FXR and TGR5

The gut microbiota plays a crucial role in regulating many physiological systems of the host, including the metabolic and immune system. Disturbances in microbiota composition are increasingly correlated with disease; however, the underlying mechanisms are not well understood. Recent evidence sugges...

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Bibliographic Details
Main Authors: Annemarie Baars, Annemarie Oosting, Jan Knol, Johan Garssen, Jeroen van Bergenhenegouwen
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Microorganisms
Subjects:
gut microbiota
dysbiosis
FXR
TGR5
bile acid dysregulation
inflammatory bowel disease
metabolic disease
probiotics
Online Access:http://www.mdpi.com/2076-2607/3/4/641

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