Management Strategies for Microalbuminuria in Diabetes Mellitus – an Overview

• Main Authors: K Kishore, A Sharma
• Format: Article
• Language: English
• Published: Nepal Medical Association 2003-07-01
• Series: Journal of Nepal Medical Association
• Online Access: http://jnma.com.np/jnma/index.php/jnma/article/view/642

Microalbuminuria (MA) in individuals with diabetes mellitus (DM) is associated with markedly reduced survival, increased risk of cardiovascular disease and is predictive of later development of an overt Diabetic Kidney Disease (DKD) and progressive renal failure. Patients with type 1 DM from 5 years after diagnosis and type 2 DM from the time of diagnosis should be screened annually for MA by sensitive stick test in spot collection or Albumin Excretion Rate (AER) in the timed collection of urine. AER. of 20-200µg/min (30- 300mg/24hr) or Albumin : Creatinine ratio (ACR) >2.5 is labelled as MA. ACE Inhibitor / Angiotensin II Receptor Blocker (ARB) therapy along with improved glycaemic control is the key to prevent or slow the progression of DKD. Key Words: Microalbuminuria, Diabetes Mellitus, Diabetic Kidney Disease.