Identification of RUNX1T1 as a potential epigenetic modifier in small‐cell lung cancer

Identification of RUNX1T1 as a potential epigenetic modifier in small‐cell lung cancer

Small‐cell lung cancer (SCLC) can be subgrouped into common ‘pure’ and rare ‘combined’ SCLC (c‐SCLC). c‐SCLC features a mixed tumor histology of both SCLC and non–small‐cell lung cancer (NSCLC). We performed targeted exome sequencing on 90 patients with SCLC, including two with c‐SCLC, and discovere...

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Bibliographic Details
Main Authors: Tian He, Gary Wildey, Karen McColl, Alyssa Savadelis, Kyle Spainhower, Cassidy McColl, Adam Kresak, Aik Choon Tan, Michael Yang, Ata Abbas, Afshin Dowlati
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Molecular Oncology
Subjects:
E2F pathway
epigenetics
exome sequencing
RUNX1T1
small‐cell lung cancer
Online Access:https://doi.org/10.1002/1878-0261.12829

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