The Numerical Study of the Hemodynamic Characteristics in the Patient-Specific Intracranial Aneurysms before and after Surgery

The patient-specific pre- and postsurgery cerebral arterial geometries in the study were reconstructed from computed tomography angiography (CTA). Three-dimensional computational fluid dynamics models were used to investigate the hemodynamic phenomena in the cerebral arteries before and after surger...

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Main Authors: Jun Soo Byun, Sun-Young Choi, Taewon Seo
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2016/4384508
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spelling doaj-b8619352c86244c8959e5ed7f13425ad2020-11-24T23:45:05ZengHindawi LimitedComputational and Mathematical Methods in Medicine1748-670X1748-67182016-01-01201610.1155/2016/43845084384508The Numerical Study of the Hemodynamic Characteristics in the Patient-Specific Intracranial Aneurysms before and after SurgeryJun Soo Byun0Sun-Young Choi1Taewon Seo2Department of Radiology, Chung-Ang University Hospital, No. 102, Heukseok-ro, Dongjak-gu, Seoul 06973, Republic of KoreaDepartment of Radiology and Medical Research Institute, School of Medicine, Ewha Womans University, No. 1071, Anyangcheon-ro, Yangcheon-gu, Seoul 07985, Republic of KoreaDepartment of Mechanical and Automotive Engineering, Andong National University, No. 1375, Gyeongdong-ro, Andong-si, Gyeongsangbuk-do 36729, Republic of KoreaThe patient-specific pre- and postsurgery cerebral arterial geometries in the study were reconstructed from computed tomography angiography (CTA). Three-dimensional computational fluid dynamics models were used to investigate the hemodynamic phenomena in the cerebral arteries before and after surgery of the aneurysm under realistic conditions. CFD simulations for laminar flow of incompressible Newtonian fluid were conducted by using commercial software, ANSYS v15, with the rigid vascular wall assumption. The study found that the flow patterns with the complex vortical structures inside the aneurysm were similar. We also found that the inflow jet streams were coming strongly in aneurysm sac in the presurgery models, while the flow patterns in postsurgery models were quite different from those in presurgery models. The average wall shear stress after surgery for model 1 was approximately three times greater than that before surgery, while it was about twenty times greater for model 2. The area of low WSS in the daughter saccular aneurysm region in model 2 is associated with aneurysm rupture. Thus the distribution of WSS in aneurysm region provides useful prediction for the risk of aneurysm rupture.http://dx.doi.org/10.1155/2016/4384508
collection DOAJ
language English
format Article
sources DOAJ
author Jun Soo Byun
Sun-Young Choi
Taewon Seo
spellingShingle Jun Soo Byun
Sun-Young Choi
Taewon Seo
The Numerical Study of the Hemodynamic Characteristics in the Patient-Specific Intracranial Aneurysms before and after Surgery
Computational and Mathematical Methods in Medicine
author_facet Jun Soo Byun
Sun-Young Choi
Taewon Seo
author_sort Jun Soo Byun
title The Numerical Study of the Hemodynamic Characteristics in the Patient-Specific Intracranial Aneurysms before and after Surgery
title_short The Numerical Study of the Hemodynamic Characteristics in the Patient-Specific Intracranial Aneurysms before and after Surgery
title_full The Numerical Study of the Hemodynamic Characteristics in the Patient-Specific Intracranial Aneurysms before and after Surgery
title_fullStr The Numerical Study of the Hemodynamic Characteristics in the Patient-Specific Intracranial Aneurysms before and after Surgery
title_full_unstemmed The Numerical Study of the Hemodynamic Characteristics in the Patient-Specific Intracranial Aneurysms before and after Surgery
title_sort numerical study of the hemodynamic characteristics in the patient-specific intracranial aneurysms before and after surgery
publisher Hindawi Limited
series Computational and Mathematical Methods in Medicine
issn 1748-670X
1748-6718
publishDate 2016-01-01
description The patient-specific pre- and postsurgery cerebral arterial geometries in the study were reconstructed from computed tomography angiography (CTA). Three-dimensional computational fluid dynamics models were used to investigate the hemodynamic phenomena in the cerebral arteries before and after surgery of the aneurysm under realistic conditions. CFD simulations for laminar flow of incompressible Newtonian fluid were conducted by using commercial software, ANSYS v15, with the rigid vascular wall assumption. The study found that the flow patterns with the complex vortical structures inside the aneurysm were similar. We also found that the inflow jet streams were coming strongly in aneurysm sac in the presurgery models, while the flow patterns in postsurgery models were quite different from those in presurgery models. The average wall shear stress after surgery for model 1 was approximately three times greater than that before surgery, while it was about twenty times greater for model 2. The area of low WSS in the daughter saccular aneurysm region in model 2 is associated with aneurysm rupture. Thus the distribution of WSS in aneurysm region provides useful prediction for the risk of aneurysm rupture.
url http://dx.doi.org/10.1155/2016/4384508
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