Oligodendroglioma anaplásico metastático

• Main Authors: Ana Sofia Patrão, Inês Sequeira, Manuel Jacóme, Joaquina Maurício
• Format: Article
• Language: English
• Published: Sociedade Galega de Medicina Interna 2018-12-01
• Series: Galicia Clínica
• Subjects: oligodendroglioma anaplásico; tumores cerebrales; metástasis
• Online Access: http://www.galiciaclinica.info/publicacion.asp?f=1598

Metastization from a brain primary tumor is a rare event. The mechanisms of metastization and the best treatment approach are still unknown. Knowledge is, so far, mostly based on case reports. We report a case of a patient with the diagnosis of an anaplastic oligodendroglioma, presenting, 9 months after the brain surgery, with spinal cord compression and pleural effusion. The patient underwent surgery for decompression and local radiotherapy to D12-L5, 30 Gy, 10 fractions and the histology confirmed metastasis of oligodendroglioma. Citology of pleural liquid confirmed the same origin. The patient started temozolomide with good clinical response and stabilization of the disease for 9 months. This is an uncommon case of bone and pleural metastization of anaplastic oligodendroglioma that had a good response to temozolomide in the metastatic setting.