Cuprizone Demyelination of the Corpus Callosum in Mice Correlates with Altered Social Interaction and Impaired Bilateral Sensorimotor Coordination

For studies of remyelination in demyelinating diseases, the cuprizone model of CC (corpus callosum) demyelination has experimental advantages that include overall size, proximity to neural stem cells of the subventricular zone, and correlation with a lesion predilection site in multiple sclerosis. I...

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Bibliographic Details
Main Authors: Norah Hibbits, Ravinder Pannu, T John Wu, Regina C Armstrong
Format: Article
Language:English
Published: SAGE Publishing 2009-08-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20090032