Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis

The stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete 1H- and 13C-NMR...

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Main Authors: Khalijah Awang, Marc Litaudon, Noel F. Thomas, A. Hamid A. Hadi, Ahmad Nazif Aziz, Mat Ropi Mukhtar
Format: Article
Language:English
Published: MDPI AG 2009-03-01
Series:Molecules
Subjects:
NMR
Online Access:http://www.mdpi.com/1420-3049/14/3/1227/
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spelling doaj-b88774293a664c09956fa8503919875f2020-11-25T01:00:51ZengMDPI AGMolecules1420-30492009-03-011431227123310.3390/molecules14031227Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandisKhalijah AwangMarc LitaudonNoel F. ThomasA. Hamid A. HadiAhmad Nazif AzizMat Ropi MukhtarThe stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete 1H- and 13C-NMR data of the tetrahydroproaporphine (–)-8,9-dihydrolinearisine (2) is also reported. The alkaloids’ structures were elucidated primarily by means of high field 1D- and 2D-NMR and HRMS spectral data. http://www.mdpi.com/1420-3049/14/3/1227/OxoproaporphineNMRPhoebe grandisAporphineDihydrolinearisine
collection DOAJ
language English
format Article
sources DOAJ
author Khalijah Awang
Marc Litaudon
Noel F. Thomas
A. Hamid A. Hadi
Ahmad Nazif Aziz
Mat Ropi Mukhtar
spellingShingle Khalijah Awang
Marc Litaudon
Noel F. Thomas
A. Hamid A. Hadi
Ahmad Nazif Aziz
Mat Ropi Mukhtar
Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
Molecules
Oxoproaporphine
NMR
Phoebe grandis
Aporphine
Dihydrolinearisine
author_facet Khalijah Awang
Marc Litaudon
Noel F. Thomas
A. Hamid A. Hadi
Ahmad Nazif Aziz
Mat Ropi Mukhtar
author_sort Khalijah Awang
title Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_short Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_full Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_fullStr Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_full_unstemmed Grandine A, a New Proaporphine Alkaloid from the Bark of Phoebe grandis
title_sort grandine a, a new proaporphine alkaloid from the bark of phoebe grandis
publisher MDPI AG
series Molecules
issn 1420-3049
publishDate 2009-03-01
description The stem bark of Phoebe grandis afforded one new oxoproaporphine; (–)-grandine A (1), along with six known isoquinoline alkaloids: (–)-8,9-dihydrolinearisine (2), boldine, norboldine, lauformine, scortechiniine A and scortechiniine B. In addition to that of the new compound, complete 1H- and 13C-NMR data of the tetrahydroproaporphine (–)-8,9-dihydrolinearisine (2) is also reported. The alkaloids’ structures were elucidated primarily by means of high field 1D- and 2D-NMR and HRMS spectral data.
topic Oxoproaporphine
NMR
Phoebe grandis
Aporphine
Dihydrolinearisine
url http://www.mdpi.com/1420-3049/14/3/1227/
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